Rabistar 20 mg (Tablet (Enteric Coated))
Unit Price: ৳ 7.00 (30's pack: ৳ 210.00)
Medicine Details
Category | Details |
---|---|
Generic | Rabeprazole sodium |
Company | Edruc limited |
Title
- Rabistar 20 mg Tablet
Categories
- Medicine
- Gastroenterology
- Pharmacology
Description
- Rabistar Gastro-resistant tablets for the treatment of acid-related disorders such as duodenal ulcer, benign gastric ulcer, gastro-esophageal reflux disease (GERD), Zollinger-Ellison Syndrome, and Helicobacter pylori eradication.
- Suppresses gastric acid secretion by inhibiting the gastric H+/K+-ATPase at the secretory surface of the gastric parietal cell.
- Dosage recommendations for different conditions and patient populations, cautioning against interactions, contraindications, side effects, precautions, and overdose effects.
- Common questions about the usage, side effects, precautions, and interactions of Rabistar 20 mg Tablet.
Indications
- Active duodenal ulcer
- Active benign gastric ulcer
- Symptomatic erosive or ulcerative gastro-esophageal reflux disease (GERD)
- Gastro-esophageal Reflux Disease Long-term Management (GERD Maintenance)
- Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
- Zollinger-Ellison Syndrome
- In combination with appropriate antibacterial therapeutic regimens for the eradication of Helicobacter pylori in patients with peptic ulcer disease.
Mode of action
- Suppresses gastric acid secretion by inhibiting the gastric H+/K+-ATPase at the secretory surface of the gastric parietal cell.
Dosage
- Recommended oral dose for active duodenal ulcer and active benign gastric ulcer is 20 mg once daily in the morning.
- Recommended oral dose for erosive or ulcerative gastro-esophageal reflux disease (GERD) is 20 mg once daily for four to eight weeks.
- For long-term management of GERD, a maintenance dose of rabeprazole sodium 20 mg or 10 mg once daily can be used depending upon patient response.
- Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD): 10 mg once daily in patients without oesophagitis. If symptom control has not been achieved during four weeks, the patient should be further investigated.
- Treatment of GERD in pediatric patients 1 to 11 years of age: 5 mg or 10 mg once daily for 12 weeks, depending on weight.
Administration
- Rabeprazole tablets should be taken in the morning, before eating, and should be swallowed whole.
Interaction
- Potential interaction with compounds whose absorption is pH dependent, such as ketoconazole or itraconazole.
- No interaction with liquid antacids was observed.
- PPIs, including rabeprazole, should not be co-administered with atazanavir.
Contraindications
- Hypersensitivity to the active substance or to any of the excipients.
- Contra-indicated in pregnancy and during breastfeeding.
Side effects
- Well-tolerated, but may cause headache, diarrhoea, abdominal pain, vomiting, constipation, dry mouth, increased or decreased appetite, muscle pain, drowsiness, dizziness.
Pregnancy cat
- US FDA pregnancy category 'C'.
- No adequate and well-controlled studies in pregnant women.
- Likely to be excreted in human milk.
Precautions
- Symptomatic response to therapy does not preclude the presence of gastric or oesophageal malignancy.
- Proton pump inhibitors may modestly increase the risk of hip, wrist, and spine fracture, especially in the elderly or in presence of other risk factors.
- Hypomagnesaemia, influence on vitamin B12 absorption, subacute cutaneous lupus erythematosus (SCLE), interference with laboratory tests.
Pediatric uses
- Not recommended for use in children due to a lack of data on safety and efficacy.
Overdose effects
- Effects are generally minimal and reversible without further medical intervention.
- No specific antidote is known.
- General supportive measures should be utilized.
Drug classes
- Proton Pump Inhibitor
Storage conditions
- Keep below 30°C temperature, away from light & moisture.
- Keep out of the reach of children.
Compound summary
- Molecular Formula: C18H21N3O3S
Commonly asked questions
- Usage, side effects, precautions, and interactions of Rabistar 20 mg Tablet.
- Overdose effects, pregnancy and lactation, special population uses, and storage conditions.
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