Rabistar 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 7.00 (30's pack: ৳ 210.00)

Medicine Details

Category Details
Generic Rabeprazole sodium
Company Edruc limited

Title

  • Rabistar 20 mg Tablet

Categories

  • Medicine
  • Gastroenterology
  • Pharmacology

Description

  • Rabistar Gastro-resistant tablets for the treatment of acid-related disorders such as duodenal ulcer, benign gastric ulcer, gastro-esophageal reflux disease (GERD), Zollinger-Ellison Syndrome, and Helicobacter pylori eradication.
  • Suppresses gastric acid secretion by inhibiting the gastric H+/K+-ATPase at the secretory surface of the gastric parietal cell.
  • Dosage recommendations for different conditions and patient populations, cautioning against interactions, contraindications, side effects, precautions, and overdose effects.
  • Common questions about the usage, side effects, precautions, and interactions of Rabistar 20 mg Tablet.

Indications

  • Active duodenal ulcer
  • Active benign gastric ulcer
  • Symptomatic erosive or ulcerative gastro-esophageal reflux disease (GERD)
  • Gastro-esophageal Reflux Disease Long-term Management (GERD Maintenance)
  • Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
  • Zollinger-Ellison Syndrome
  • In combination with appropriate antibacterial therapeutic regimens for the eradication of Helicobacter pylori in patients with peptic ulcer disease.

Mode of action

  • Suppresses gastric acid secretion by inhibiting the gastric H+/K+-ATPase at the secretory surface of the gastric parietal cell.

Dosage

  • Recommended oral dose for active duodenal ulcer and active benign gastric ulcer is 20 mg once daily in the morning.
  • Recommended oral dose for erosive or ulcerative gastro-esophageal reflux disease (GERD) is 20 mg once daily for four to eight weeks.
  • For long-term management of GERD, a maintenance dose of rabeprazole sodium 20 mg or 10 mg once daily can be used depending upon patient response.
  • Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD): 10 mg once daily in patients without oesophagitis. If symptom control has not been achieved during four weeks, the patient should be further investigated.
  • Treatment of GERD in pediatric patients 1 to 11 years of age: 5 mg or 10 mg once daily for 12 weeks, depending on weight.

Administration

  • Rabeprazole tablets should be taken in the morning, before eating, and should be swallowed whole.

Interaction

  • Potential interaction with compounds whose absorption is pH dependent, such as ketoconazole or itraconazole.
  • No interaction with liquid antacids was observed.
  • PPIs, including rabeprazole, should not be co-administered with atazanavir.

Contraindications

  • Hypersensitivity to the active substance or to any of the excipients.
  • Contra-indicated in pregnancy and during breastfeeding.

Side effects

  • Well-tolerated, but may cause headache, diarrhoea, abdominal pain, vomiting, constipation, dry mouth, increased or decreased appetite, muscle pain, drowsiness, dizziness.

Pregnancy cat

  • US FDA pregnancy category 'C'.
  • No adequate and well-controlled studies in pregnant women.
  • Likely to be excreted in human milk.

Precautions

  • Symptomatic response to therapy does not preclude the presence of gastric or oesophageal malignancy.
  • Proton pump inhibitors may modestly increase the risk of hip, wrist, and spine fracture, especially in the elderly or in presence of other risk factors.
  • Hypomagnesaemia, influence on vitamin B12 absorption, subacute cutaneous lupus erythematosus (SCLE), interference with laboratory tests.

Pediatric uses

  • Not recommended for use in children due to a lack of data on safety and efficacy.

Overdose effects

  • Effects are generally minimal and reversible without further medical intervention.
  • No specific antidote is known.
  • General supportive measures should be utilized.

Drug classes

  • Proton Pump Inhibitor

Storage conditions

  • Keep below 30°C temperature, away from light & moisture.
  • Keep out of the reach of children.

Compound summary

  • Molecular Formula: C18H21N3O3S

Commonly asked questions

  • Usage, side effects, precautions, and interactions of Rabistar 20 mg Tablet.
  • Overdose effects, pregnancy and lactation, special population uses, and storage conditions.

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