Legaba 25 mg (Capsule)

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Pregabalin
Company Apex pharmaceuticals ltd
Also available as
Legaba 50 mg capsule

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

  • Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
  • Binds to the alpha2-delta site in central nervous system tissues

Dosage

  • Maximum recommended dose of Pregabalin is 100 mg three times a day for DPN
  • Recommended dose of Pregabalin is 75 to 150 mg two times a day for PHN
  • Recommended dose of Pregabalin is 300 to 450 mg/day for fibromyalgia
  • Recommended dose range of Pregabalin is 150 to 600 mg/day for spinal cord injury

Administration

  • Oral route of administration
  • Should be swallowed whole and should not be split, crushed or chewed
  • Pregabalin CR tablet should be administered after an evening meal

Drug Interaction

  • Legaba is unlikely to be involved in significant pharmacokinetic drug interactions

Contraindications

  • Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components

Side Effects

  • Most common side effects in adults are dizziness, somnolence, dry mouth, edema, blurred vision, weight gain and thinking abnormal
  • Most common side effects in pediatric patients for the treatment of partial onset seizures are increased weight and increased appetite

Pregnancy & Lactation

  • No adequate and well-controlled studies with pregabalin in pregnant women
  • Breastfeeding is not recommended during treatment with pregabalin

Precautions & Warnings

  • Angioedema can occur and may be associated with life threatening respiratory compromise
  • Antiepileptic drugs, including Legaba, increase the risk of suicidal thoughts or behavior
  • Respiratory depression may occur with Legaba when used with concomitant CNS depressants
  • Legaba may cause dizziness and somnolence and impair patients' ability to drive or operate machinery

Use in Special Populations

  • Safety and effectiveness in pediatric patients have not been established for several indications

Overdose Effects

  • Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block
  • No specific antidote

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage Conditions

  • Keep in a cool & dry place (below 30°C), protected from light & moisture

Chemical Structure

  • Molecular Formula: C8H17NO2

Common Questions

  • What is Legaba 25 mg Capsule?
  • How long do I need to use Legaba 25 mg Capsule before I see improvement in my condition?
  • At what frequency do I need to use Legaba 25 mg Capsule?
  • Should I use Legaba 25 mg Capsule empty stomach, before food or after food?
  • What are the instructions for the storage and disposal of Legaba 25 mg Capsule?
  • Does Legaba 25 mg Capsule work in the same way for each disease?
  • How long do I need to take Legaba 25 mg Capsule?
  • Is it necessary to continue taking Legaba 25 mg Capsule even if I feel fine?
  • Can I take Diazepam and Legaba 25 mg Capsule together?
  • Can the use of Legaba 25 mg Capsule cause weight gain?
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