Rosuva 10 mg (Tablet)

Unit Price: ৳ 20.13 (3 x 10: ৳ 603.90)
Strip Price: ৳ 201.30

Medicine Details

Category Details
Generic Rosuvastatin calcium
Company Square pharmaceuticals plc
Also available as
Rosuva 5 mg tablet Rosuva 20 mg tablet

Title

  • Rosuva 10 mg Tablet

Categories

  • Medicine
  • Pharmaceutical

Description

  • Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme that converts 3-hydroxy-3-methyl glutaryl coenzyme A to mevalonate, a precursor of cholesterol.
  • Rosuva is generally well tolerated. The most frequent adverse events thought to be related to Rosuva were headache, myalgia, constipation, asthenia, abdominal pain and nausea.

Attributes

  • Indications:
    • Heterozygous Hypercholesterolemia (Familial and Non familial)
    • Homozygous Hypercholesterolemia (Familial)
    • Mixed Dyslipidemia (Fredrickson Type IIa and IIb)
    • Primary prevention of cardiovascular disease
  • Pharmacology:
    • Increases the number of hepatic LDL receptors on the cell surface to enhance uptake and catabolism of LDL
    • Inhibits hepatic synthesis of VLDL, which reduces the total number of VLDL and LDL particles
  • Dosage Range: 5-40 mg once daily
  • Maximum Dose: 40 mg once daily for patients not reaching LDL-C goal with 20 mg
  • Starting Dose for HoFH: 20 mg/day
  • Pediatric Dose for HeFH:
    • 5-10 mg/day for patients 8 to less than 10 years age
    • 5-20 mg/day for patients 10 to 17 years of age
  • Pediatric Dose for HoFH: 20 mg/day for patients 7 to 17 years of age
  • Administration: Can be taken with or without food, at any time of day
  • Drug Interactions:
    • Cyclosporine increases Rosuva exposure
    • Gemfibrosil combination should be avoided
    • Lopinavir/Ritonavir or atazanavir/ritonavir combination increases Rosuva exposure
    • Coumarin anticoagulants combination prolongs international normalized ratio (INR)
    • Concomitant lipid-lowering therapies use with fibrates and niacin products may increase the risk of skeletal muscle effects.
  • Contraindications:
    • Known hypersensitivity to product components
    • Liver disease, including unexplained persistent elevations in hepatic transaminase levels
    • Pregnant women and women who may become pregnant
    • Nursing mothers
  • Side Effects:
    • Headache
    • Myalgia
    • Constipation
    • Asthenia
    • Abdominal pain
    • Nausea
  • Pregnancy & Lactation: Safety in pregnant women has not been established. It is not known whether Rosuvastatin is excreted in human milk.
  • Precautions & Warnings:
    • Risks increase with use of 40 mg dose, advanced age (>65 years), hypothyroidism, renal impairment and combination use with certain other drugs
    • Promptly report unexplained muscle pain, tenderness or weakness
  • Use in Special Populations: The safety and effectiveness in pediatric patients have not been established
  • Therapeutic Class:
    • Other Anti-anginal & Anti-ischaemic drugs
    • Statins
  • Storage Conditions: Keep below 30°C temperature, protected from light & moisture. Keep out of the reach of children.
  • Molecular Formula: C22H28FN3O6S
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-970-rosuvastatin-calcium-chemical-structure-UjXgzBvpDHiLnIP3gZua.svg
  • FAQs:
    • What is Rosuva 10 mg Tablet?
    • What are the uses of Rosuva 10 mg Tablet?
    • What are the side effects of Rosuva 10 mg Tablet?
    • For how long should I take Rosuva 10 mg Tablet?
    • Does Rosuva 10 mg Tablet cause weight gain?
    • Does Rosuva 10 mg Tablet make you tired?
    • Should Rosuva 10 mg Tablet be taken at night?
    • What foods should be avoided when taking Rosuva 10 mg Tablet?
    • How do I know whether Rosuva 10 mg Tablet is beneficial for me or not?
    • Can Rosuva 10 mg Tablet cause memory loss?
    • Is it true that Rosuva 10 mg Tablet can cause diabetes?
    • Can I take alcohol with Rosuva 10 mg Tablet?
    • Can Rosuva 10 mg Tablet cause muscle problems or muscle injury?
    • Quick Tips

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