Broklin CR 165 mg (Tablet (Controlled Release))

Unit Price: ৳ 35.00 (2 x 10: ৳ 700.00)
Strip Price: ৳ 350.00

Medicine Details

Category Details
Generic Pregabalin
Company One pharma ltd
Also available as
Broklin 50 mg capsule Broklin 75 mg capsule Broklin cr 825 mg tablet

Title and Categories

  • Broklin CR 165 mg Tablet
  • Medicine
  • Neuropathic Pain
  • Postherpetic Neuralgia
  • Seizures
  • Fibromyalgia
  • Spinal Cord Injury
  • Anticonvulsant

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Mode of Action

Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), binds with high affinity to the alpha2-delta site in central nervous system tissues

Dosage

  • DPN Adult:
    • 50-100 mg three times a day, maximum 300 mg/day
    • Begin CR capsule at 165 mg once daily, increase to 330 mg once daily
  • PHN Adult:
    • 75-150 mg two times a day or 50-100 mg three times a day, maximum 300 mg/day
    • Begin CR capsule at 165 mg once daily, increase to 330 mg once daily
  • Fibromyalgia:
    • 300-450 mg/day
    • Begin at 75 mg two times a day, increase to 150 mg two times a day
  • Spinal Cord Injury:
    • 150-600 mg/day
    • Start at 75 mg two times a day, increase to 150 mg two times a day
  • Conversion From Pregabalin Capsules to Pregabalin CR Capsule Tablet: Dosing equivalence provided

Administration

  • Route: Oral, with or without food
  • CR Tablet: Administered after an evening meal, swallow whole, not split, crushed, or chewed

Interaction

  • Medication: Unlikely to have significant pharmacokinetic drug interactions
  • Food and Others: Not applicable

Contraindications

Hypersensitivity to Pregabalin or any of its components

Side Effects

  • Adults:
    • Dizziness
    • Somnolence
    • Dry mouth
    • Edema
    • Blurred vision
    • Weight gain
    • Difficulty with concentration/attention
  • Pediatric Patients:
    • Increased weight
    • Increased appetite

Pregnancy & Lactation

No adequate and well-controlled studies, small amounts detected in the milk of lactating women, breastfeeding not recommended

Precautions & Warnings

  • Angioedema
  • Hypersensitivity reactions
  • Increased risk of suicidal thoughts or behavior
  • Respiratory depression potential
  • May cause dizziness and somnolence
  • Peripheral edema caution
  • Coadministration precautions

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