Ruvastin 5 mg (Tablet)

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Indications

  • Heterozygous Hypercholesterolemia (Familial and Non familial)
  • Homozygous Hypercholesterolemia (Familial)
  • Mixed Dyslipidemia (Fredrickson Type IIa and IIb)
  • Primary prevention of cardiovascular disease

Pharmacology

Selective and competitive inhibitor of HMG-CoA reductase, increases hepatic LDL receptors, inhibits hepatic synthesis of VLDL

Dosage

5-40 mg once daily, 40 mg dose for patients not reaching LDL-C goal with 20 mg, specific doses for pediatric patients

Administration

Can be taken with or without food, at any time of day

Interaction

  • Cyclosporine increases exposure, Gemfibrosil combination should be avoided, Lopinavir/Ritonavir increases exposure, Coumarin anticoagulants prolong INR, Concomitant lipid-lowering therapies increase risk of skeletal muscle effects

Contraindications

  • Known hypersensitivity to product components
  • Liver disease with unexplained persistent elevations in hepatic transaminase levels
  • Pregnant women and women who may become pregnant
  • Nursing mothers

Side Effects

  • Headache
  • Myalgia
  • Constipation
  • Asthenia
  • Abdominal pain
  • Nausea

Pregnancy & Lactation

Safety in pregnant women not established, excretion in human milk unknown

Precautions & Warnings

  • Skeletal muscle effects increase with 40 mg dose, advanced age, hypothyroidism, renal impairment, combination use with specific drugs
  • Liver enzyme abnormalities and monitoring required

Use in Special Populations

Safety and effectiveness in pediatric patients not established

Therapeutic Class

Other Anti-anginal & Anti-ischaemic drugs, Statins

Storage Conditions

Keep below 30°C temperature, protected from light & moisture, keep out of the reach of children

Chemical Structure

  • Molecular Formula: C22H28FN3O6S
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-970-rosuvastatin-calcium-chemical-structure-UjXgzBvpDHiLnIP3gZua.svg

Common Questions about Ruvastin 5 mg Tablet

  • Uses
  • Side effects
  • Duration of use
  • Effect on weight
  • Effect on tiredness
  • Administration timing
  • Foods to avoid
  • Beneficial effects
  • Memory loss risk
  • Diabetes risk
  • Alcohol consumption caution
  • Muscle problems or injury risk
  • Quick Tips

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