Ruvastin 10 mg (Tablet)
Unit Price: ৳ 24.00 (3 x 10: ৳ 720.00)
Strip Price: ৳ 240.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rosuvastatin calcium |
| Company | Aristopharma ltd |
| Also available as |
Indications
- Heterozygous Hypercholesterolemia (Familial and Non familial)
- Homozygous Hypercholesterolemia (Familial)
- Mixed Dyslipidemia (Fredrickson Type IIa and IIb)
- Primary prevention of cardiovascular disease
Pharmacology
Selective and competitive inhibitor of HMG-CoA reductase
Dose range
5-40 mg once daily
Starting dose for HoFH
20 mg/day
Pediatric dose for HeFH
- 5-10 mg/day for patients 8 to less than 10 years age
- 5-20 mg/day for patients 10 to 17 years of age
Administration
Can be taken with or without food, at any time of day
Interaction
- Cyclosporine increases Ruvastin exposure. Ruvastin dose should be limited to 5 mg once daily
- Gemfibrosil combination should be avoided. If used together, Ruvastin dose should be limited to 10 mg once daily
- Lopinavir/Ritonavir or atazanavir/ritonavir combination increases Ruvastin exposure. Ruvastin dose should be to 10 mg once daily
- Coumarin anticoagulants combination prolongs international normalized ratio (INR). Stable INR should be achieved prior to starting Ruvastin. INR should be monitored frequently until stable upon initiation or alteration of Ruvastin therapy
- Concomitant lipid-lowering therapies use with fibrates and niacin products may increase the risk of skeletal muscle effects
Contraindications
- Known hypersensitivity to product components
- Liver disease, which may include unexplained persistent elevations in hepatic transaminase levels
- Pregnant women and women who may become pregnant
- Nursing mothers
Side Effects
- Headache
- Myalgia
- Constipation
- Asthenia
- Abdominal pain
- Nausea
Pregnancy & Lactation
Safety in pregnant women has not been established. It is not known whether Rosuvastatin is excreted in human milk or not
Precautions & Warnings
- Skeletal muscle effects (e.g., myopathy and rhabdomyolysis)
- Liver enzyme abnormalities and monitoring
Use in Special Populations
The safety and effectiveness in pediatric patients have not been established
Therapeutic Class
- Other Anti-anginal & Anti-ischaemic drugs
- Statins
Storage Conditions
Keep below 30°C temperature, protected from light & moisture. Keep out of the reach of children
Chemical Structure
- Molecular Formula: C22H28FN3O6S
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-970-rosuvastatin-calcium-chemical-structure-UjXgzBvpDHiLnIP3gZua.svg