Lemodip 2.5 mg (Tablet)
Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Levamlodipine maleate |
| Company | Incepta pharmaceuticals ltd |
| Also available as | Lemodip 125 mg tabletLemodip 5 mg tablet |
Indications
- Treatment of hypertension
- Lowering blood pressure
- Reducing risk of cardiovascular events
- Stroke prevention
- Myocardial infarction prevention
Pharmacology
- Dihydropyridine calcium antagonist
- Inhibition of calcium ion influx
- Selective effect on vascular smooth muscle cells
- Volume of distribution similar to amlodipine
- Metabolized by CYP3A4
- Excretion in urine
Dosage & Administration
- Oral route of administration
- Usual initial dose of 2.5 mg once daily
- Maximum dose of 5 mg once daily
- Reduced dose for elderly and hepatic insufficiency
- Titration for dosage adjustment
- Pediatric dose of 1.25 mg to 2.5 mg once daily
Interaction
- Increased systemic exposure with CYP3A inhibitors
- No quantitative effects with CYP3A inducers
- Increased systemic exposure of simvastatin
- Increased systemic exposure of immunosuppressants
- Can be taken with or without food
- Avoid grapefruit products and natural licorice
Contraindications
- Known sensitivity to amlodipine
Side Effects
- Difficulty in breathing
- Dizziness
- Reflex Tachycardia
- Hypotension
- Abdominal Pain
- Edema
- Diarrhea (rare)
- Back pain (rare)
- Headache (rare)
- Fatigue (rare)
- Nausea (rare)
Pregnancy & Lactation
- Limited data on drug-associated risk in pregnancy
- No observed adverse effects on breastfed infants
Precautions & Warnings
- Possible symptomatic hypotension
- Worsening angina and acute myocardial infarction
- Slow titration for patients with hepatic impairment
Overdose Effects
- Excessive peripheral vasodilation
- Marked hypotension
- Possibly reflex tachycardia
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Cool and dry storage
- Protection from light and moisture
- Keep out of reach of children