Nabumet 1000 mg (Tablet)
Unit Price: ৳ 30.00 (2 x 6: ৳ 360.00)
Strip Price: ৳ 180.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Nabumetone |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Indications
- Relief of signs and symptoms of osteoarthritis
- Relief of signs and symptoms of rheumatoid arthritis
Pharmacology
- Non-steroidal anti-inflammatory drug (NSAID)
- Exhibits anti-inflammatory properties
- Exhibits analgesic properties
- Exhibits antipyretic properties
- Prodrug
- Undergoes hepatic biotransformation
Dosage & Administration
- Available in 500 mg & 750 mg Tablet
- Available in 1000 mg Tablet
- Recommended starting dose: 1000 mg
- Maximum daily dose: 2000 mg
- Can be taken with or without food
- Different dosages for renal insufficiency
- Not studied in pediatric patients
Interaction
- May diminish the antihypertensive effect of ACE-inhibitors
Contraindications
- Hypersensitivity to nabumetone or its excipients
- History of asthma, urticaria, or allergic-type reactions to aspirin or other NSAIDs
- Contraindicated for peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery
Side Effects
- Gastrointestinal effects
- Central Nervous System effects
- Dermatologic effects
- Special Senses effects
- Miscellaneous effects
Pregnancy & Lactation
- Pregnancy Category C
- Not recommended during the third trimester
- Not recommended for use in nursing mothers
Precautions & Warnings
- Associated with renal papillary necrosis and other abnormal renal pathology
- Associated with reduced renal blood flow in certain patients
- Discontinuation may lead to recovery
Overdose Effects
- Symptoms include lethargy, drowsiness, nausea, vomiting, and epigastric pain
- Rare but serious effects like hypertension, acute renal failure, respiratory depression, and coma
- No specific antidotes
- Management by symptomatic and supportive care
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
Storage Conditions
- Store in a cool and dry place
- Keep away from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C15H16O2
Common Questions about Nabumet 1000 mg Tablet
- Usage for pain and inflammation relief
- Use with food or milk to prevent upset stomach
- Caution regarding dizziness, drowsiness, and visual disturbances
- Avoidance of alcohol consumption
- Monitoring of kidney function, liver function, and blood components
Other Attribute
- NSAID with potential benefits and risks
- Inhibition of prostaglandin synthesis may be involved in the anti-inflammatory effect
- Maximum starting doses for patients with renal insufficiency
- Limited specific information on pediatric use