Cardinor Plus 2.5 mg+6.25 mg (Tablet)

Indications

• Treatment of Hypertension

Pharmacology

• Bisoprolol Fumarate and Hydrochlorothiazide combination for hypertension treatment
• Antihypertensive effects of the agents
• Mode of action of Bisoprolol Fumarate and Hydrochlorothiazide

Dosage & Administration

• Effective doses of Bisoprolol and Hydrochlorothiazide
• Initial therapy guidelines
• Replacement therapy guidance
• Therapy guided by clinical effect

Interaction

• Potential interaction with other antihypertensive agents
• Interaction with beta-blocking agents
• Cautions for concurrent therapy with clonidine
• Caution when combined with myocardial depressants or AV conduction inhibitors

Contraindications

• Contradictions for cardiogenic shock, cardiac failure, AV block, sinus bradycardia, anuria, and hypersensitivity

Side Effects

• Mild and transient side effects
• Fatigue, dizziness, headache, bradycardia, arrhythmia, palpitations, cold extremities, gastrointestinal effects, etc.

Pregnancy & Lactation

• Pregnancy category C
• Use in nursing mothers
• Excretion in human breast milk
• Consideration for potential adverse reactions in nursing infants

Precautions & Warnings

• Risk of hyperuricemia or acute gout
• Warning signs of fluid and electrolyte imbalance
• Risk of hypokalemia
• Gradual withdrawal of therapy over 2 weeks

Overdose Effects

• Expected signs of overdose with beta-blocker
• Potential signs and symptoms of thiazide diuretics overdose

Therapeutic Class

• Combined antihypertensive preparations

Storage Conditions

• Temperature and storage guidelines
• Protection from light and moisture
• Keep out of the reach of children

Related Brands

• Cardinor Plus 5 mg+6.25 mg (Tablet) - labaid-pharma-ltd
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• Prelizer-HTZ 5 mg+6.25 mg (Tablet) - radiant-pharmaceuticals-ltd