Voxamin XR 100 mg (Capsule (Extended Release))
Unit Price: ৳ 30.00 (3 x 6: ৳ 540.00)
Strip Price: ৳ 180.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluvoxamine maleate |
| Company | Renata limited |
| Also available as |
Indications
- Obsessive-Compulsive Disorder
- Depressive illness
- Panic Disorder
- Eating Disorders
- Chronic Tension Headache
Pharmacology
Inhibition of CNS neuronal uptake of serotonin, enhancement of serotonin actions on 5HT1A autoreceptors, virtually no affinity for various receptors
Dosage & Administration
- Adults: Recommended starting dose of 50 mg, titration within a range of 100 to 300 mg/day
- Pediatric Population: Recommended starting dose for ages 8-17 years of 25 mg, titration within a range of 50 to 200 mg/day
- Elderly or Hepatically Impaired Patients: Decreased clearance observed, may require modification of initial dose and subsequent titration
Interaction
- Inhibition of CYP1A2, CYP2C9, CYP3A4, and CYP2C19
- Elevated carbamazepine levels and symptoms of toxicity with coadministration
- Rare reports of weakness, hyperreflexia, and incoordination following use of an SSRI and sumatriptan
- Increased tacrine C max and AUC with coadministration resulting in nausea, vomiting, sweating, and diarrhea
- Significantly increased plasma TCA levels with coadministration of TCAs
- Severe vomiting with coadministration of tryptophan
- Bradycardia with coadministration of diltiazem
- Dose reduction and cautious titration advised with coadministration of propranolol or metoprolol
Contraindications
- Coadministration of tizanidine, thioridazine, alosetron, pimozide
- Contraindicated with MAOIs and linezolid or intravenous methylene blue
Side Effects
- Nausea
- Somnolence
- Insomnia
- Asthenia
- Nervousness
- Dyspepsia
- Abnormal ejaculation
- Sweating
- Anorexia
- Tremor
- Vomiting
- Anorgasmia
- Decreased libido
- Dry mouth
- Rhinitis
- Taste perversion
- Urinary frequency
- Agitation
- Depression
- Dysmenorrhea
- Flatulence
- Hyperkinesia
- Rash
Pregnancy & Lactation
Consider risks and benefits, potential for complications in infants exposed late in pregnancy, secreted in human breast milk
Precautions & Warnings
Use with caution in patients with specific medical history or conditions, may impair performance of skilled tasks such as driving
Therapeutic Class
SSRIs & related anti-depressant drugs
Storage Conditions
Keep below 30°C, away from light & moisture, out of the reach of children