Seroprex 25 mg (Tablet)
Unit Price: ৳ 3.00 (3 x 10: ৳ 90.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Quetiapine fumarate |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Treatment of Acute and chronic psychoses
- Treatment of schizophrenia
- Treatment of Bipolar Disorder
- Maintenance treatment of bipolar I disorder
- Treatment of depressive episodes associated with bipolar disorder
Pharmacology
- Antagonist at multiple neurotransmitter receptors
- Belonging to a chemical class, the dibenzothiazepine derivatives
- Serotonin 5HT1A and 5HT2 antagonist
- Dopamine D1 and D2 antagonist
- Histamine H1 antagonist
- Adrenergic alpha1 and alpha2 antagonist
- Mechanism of action is unknown
Dosage & Administration
- Administered twice daily
- Dosage titration for different indications
- Usual effective dose range 300-450 mg/day
- Usual effective dose range 400-800 mg/day
- Usual dose 300 mg/day
- Usual effective dose range of 400 to 800mg/day
Interaction
- Caution with medicines causing electrolyte imbalance
- Caution with medicines increasing QT interval
- Co-administration effects with thioridazine, carbamazepine, and phenytoin
Contraindications
- Contra-indicated in patients hypersensitive to it
Side Effects
- Somnolence
- Dizziness
- Dry mouth
- Elevated serum triglyceride levels
- Decreased HDL cholesterol
- Weight gain
- Extrapyramidal symptoms
Pregnancy & Lactation
- Safety and efficacy not established in human pregnancy
- Use only if benefits justify potential risks
- Avoid breastfeeding while taking the medicine
Precautions & Warnings
- Risk of suicidal thoughts and self-harm
- Caution in patients with cardiovascular or cerebrovascular disease
- Caution in patients with history of seizures
- Consider dose reduction for tardive dyskinesia
- Caution in patients with family history of QT prolongation
Use in Special Populations
- Caution in the elderly
- Not indicated for use in children and adolescents below 18 years of age
Overdose Effects
- Survival reported in acute overdoses of up to 30 grams
- No specific antidote
- Intensive care procedures recommended
- Treatment of refractory hypotension
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Keep out of the reach of children
- Do not use after expiry date
- Store in a cool and dry place away from light