Seroprex 25 mg (Tablet)

Unit Price: ৳ 3.00 (3 x 10: ৳ 90.00)
Strip Price: ৳ 30.00

Medicine Details

Category Details
Generic Quetiapine fumarate
Company Square pharmaceuticals plc
Also available as
Seroprex 100 mg tablet

Indications

  • Treatment of Acute and chronic psychoses
  • Treatment of schizophrenia
  • Treatment of Bipolar Disorder
  • Maintenance treatment of bipolar I disorder
  • Treatment of depressive episodes associated with bipolar disorder

Pharmacology

  • Antagonist at multiple neurotransmitter receptors
  • Belonging to a chemical class, the dibenzothiazepine derivatives
  • Serotonin 5HT1A and 5HT2 antagonist
  • Dopamine D1 and D2 antagonist
  • Histamine H1 antagonist
  • Adrenergic alpha1 and alpha2 antagonist
  • Mechanism of action is unknown

Dosage & Administration

  • Administered twice daily
  • Dosage titration for different indications
  • Usual effective dose range 300-450 mg/day
  • Usual effective dose range 400-800 mg/day
  • Usual dose 300 mg/day
  • Usual effective dose range of 400 to 800mg/day

Interaction

  • Caution with medicines causing electrolyte imbalance
  • Caution with medicines increasing QT interval
  • Co-administration effects with thioridazine, carbamazepine, and phenytoin

Contraindications

  • Contra-indicated in patients hypersensitive to it

Side Effects

  • Somnolence
  • Dizziness
  • Dry mouth
  • Elevated serum triglyceride levels
  • Decreased HDL cholesterol
  • Weight gain
  • Extrapyramidal symptoms

Pregnancy & Lactation

  • Safety and efficacy not established in human pregnancy
  • Use only if benefits justify potential risks
  • Avoid breastfeeding while taking the medicine

Precautions & Warnings

  • Risk of suicidal thoughts and self-harm
  • Caution in patients with cardiovascular or cerebrovascular disease
  • Caution in patients with history of seizures
  • Consider dose reduction for tardive dyskinesia
  • Caution in patients with family history of QT prolongation

Use in Special Populations

  • Caution in the elderly
  • Not indicated for use in children and adolescents below 18 years of age

Overdose Effects

  • Survival reported in acute overdoses of up to 30 grams
  • No specific antidote
  • Intensive care procedures recommended
  • Treatment of refractory hypotension

Therapeutic Class

  • Atypical neuroleptic drugs

Storage Conditions

  • Keep out of the reach of children
  • Do not use after expiry date
  • Store in a cool and dry place away from light

Related Brands