Sinapride 1 mg (Tablet)
Unit Price: ৳ 14.00 (2 x 10: ৳ 280.00)
Strip Price: ৳ 140.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Prucalopride succinate |
| Company | Ibn sina pharmaceuticals ltd |
| Also available as |
Indications
- Symptomatic treatment of chronic constipation in adults
Pharmacology
- Selective stimulator of the 5-HT4 receptors
- Acts on smooth muscle cells
- Stimulates motility in the gastrointestinal tract
Dosage & Administration
- 2 mg once daily for adults
- Start with 1 mg once daily for older people
- Not recommended for children and adolescents under 18 years
Interaction
- Low interaction potential
- Therapeutic concentrations not expected to affect CYP-mediated metabolism
- Potential interactions with potent inhibitors of P-gp
Contraindications
- Hypersensitivity to the active substance or excipients
- Renal impairment requiring dialysis
Side Effects
- Headache
- Gastrointestinal symptoms (abdominal pain, nausea, diarrhea)
Pregnancy & Lactation
- Not recommended during pregnancy
- Effective contraception advised for women of childbearing potential
- Not recommended during breastfeeding
Precautions & Warnings
- Renal excretion is the main route of elimination
- Caution in prescribing to patients with severe hepatic impairment
- Possible reduced efficacy of oral contraceptives during severe diarrhea
Use in Special Populations
- 1 mg once daily for patients with severe renal impairment
- Start with 1 mg once daily for patients with severe hepatic impairment
Overdose Effects
- Symptomatic treatment for overdose
- Correction of electrolyte disturbances in case of extensive fluid loss
Therapeutic Class
- Osmotic purgatives
Storage Conditions
- Store at room temperature below 30°C
- Dispense in original bottle