Vorier 200 mg (Tablet)
Unit Price: ৳ 120.00 (1 x 10: ৳ 1,200.00)
Strip Price: ৳ 1,200.00
Medicine Details
Category | Details |
---|---|
Generic | Voriconazole |
Company | One pharma ltd |
Indications
- Treatment for invasive aspergillosis
- Treatment for candidemia (nonneutropenic)
- Treatment for disseminated candidiasis in skin, abdomen, kidney, bladder wall, and wounds
- Treatment for esophageal candidiasis
- Treatment for serious infections caused by Scedosporium apiospermum and Fusarium Species
- Indicated for patients intolerant of, or refractory to other therapy
Pharmacology
Binds and inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-alpha sterol demethylase
Dosage & Administration
- Oral administration at least one hour before or after a meal
- Different loading doses and maintenance doses based on body weight
- Injection administration for invasive aspergillosis, candidemia, Scedosporiosis, and Fusariosis
Interaction
- Adjust dosage and monitor for adverse reactions with CYP3A4, CYP2C9, and CYP2C19 inhibitors and inducers
- Increase maintenance dosage with co-administration of Phenytoin or Efavirenz
Contraindications
- Hypersensitivity to Voriconazole or any other components of the drug
- Co-administration with terfenadine, astemizole, cisapride, pimozide, or quinidine
- Co-administration with rifampin, carbamazepine, long-acting barbiturates, efavirenz, ritonavir, rifabutin, ergot alkaloids, and St. John's Wort
Side Effects
- Abdominal pain
- Anemia
- Blurred vision
- Headache
- Chest pain
- Nausea
- Diarrhea
Pregnancy & Lactation
Should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus
Precautions & Warnings
Long term exposure greater than 180 days requires careful assessment of the benefit-risk balance
Use in Special Populations
Efficacy in children under 12 years of age is not established
Overdose Effects
No data on overdose effects
Therapeutic Class
Other Antifungal preparations
Reconstitution
Instructions for reconstituting suspension
Storage Conditions
Store in a dry place, below 25°C temperature, and protected from light