Vorier 200 mg (Tablet)

Unit Price: ৳ 120.00 (1 x 10: ৳ 1,200.00)
Strip Price: ৳ 1,200.00

Medicine Details

Category Details
Generic Voriconazole
Company One pharma ltd

Indications

  • Treatment for invasive aspergillosis
  • Treatment for candidemia (nonneutropenic)
  • Treatment for disseminated candidiasis in skin, abdomen, kidney, bladder wall, and wounds
  • Treatment for esophageal candidiasis
  • Treatment for serious infections caused by Scedosporium apiospermum and Fusarium Species
  • Indicated for patients intolerant of, or refractory to other therapy

Pharmacology

Binds and inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-alpha sterol demethylase

Dosage & Administration

  • Oral administration at least one hour before or after a meal
  • Different loading doses and maintenance doses based on body weight
  • Injection administration for invasive aspergillosis, candidemia, Scedosporiosis, and Fusariosis

Interaction

  • Adjust dosage and monitor for adverse reactions with CYP3A4, CYP2C9, and CYP2C19 inhibitors and inducers
  • Increase maintenance dosage with co-administration of Phenytoin or Efavirenz

Contraindications

  • Hypersensitivity to Voriconazole or any other components of the drug
  • Co-administration with terfenadine, astemizole, cisapride, pimozide, or quinidine
  • Co-administration with rifampin, carbamazepine, long-acting barbiturates, efavirenz, ritonavir, rifabutin, ergot alkaloids, and St. John's Wort

Side Effects

  • Abdominal pain
  • Anemia
  • Blurred vision
  • Headache
  • Chest pain
  • Nausea
  • Diarrhea

Pregnancy & Lactation

Should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus

Precautions & Warnings

Long term exposure greater than 180 days requires careful assessment of the benefit-risk balance

Use in Special Populations

Efficacy in children under 12 years of age is not established

Overdose Effects

No data on overdose effects

Therapeutic Class

Other Antifungal preparations

Reconstitution

Instructions for reconstituting suspension

Storage Conditions

Store in a dry place, below 25°C temperature, and protected from light

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