Ardance 10 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Empagliflozin |
| Company | Pharmacil limited |
| Also available as |
Indications
- Adjunct to diet and exercise for glycemic control in adults with type 2 diabetes mellitus
- To reduce risk of cardiovascular death in adult patients with type 2 diabetes mellitus and established cardiovascular disease
Pharmacology
Sodium glucose co-transporter-2 (SGLT-2) inhibitor that reduces renal glucose reabsorption and lowers the renal threshold for glucose, resulting in increased glucose excretion, weight loss, and reduced hyperglycemia
Dosage & Administration
Recommended dose of 10 mg once daily, may be increased to 25 mg once daily in tolerant patients
Interactions
- Increased urine volume with diuretics
- Increased risk of hypoglycemia with insulin or insulin secretagogues
- Not recommended for monitoring glycemic control with urine glucose tests or 1,5-AG assay
Contraindications
History of serious hypersensitivity to Empagliflozin or any of its ingredients, severe renal impairment, end-stage renal disease, or dialysis
Side Effects
- Urinary tract infections
- Female genital mycotic infections
- Dehydration
- Hypotension
- Weakness
- Dizziness
- Increased thirstiness
Pregnancy & Lactation
- Not adequately studied in pregnant women
- Use only if potential benefit justifies potential risk to fetus
- Not recommended during breastfeeding
Precautions & Warnings
Assessment of renal function recommended prior to initiation, avoid in patients with eGFR less than 45 ml/min/1.73 m^2
Overdose Effects
Supportive measures for overdose, hemodialysis not studied for removal
Therapeutic Class
Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors
Storage Conditions
Keep below 30°C, protected from light & moisture, keep out of reach of children
Chemical Structure
- Molecular Formula: C23H27ClO7
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-1275-empagliflozin-chemical-structure-Z3X0mrA6UvgM682Jgp8K.svg
Common Questions about Ardance 10 mg Tablet
- What is Ardance 10 mg Tablet?: SGLT-2 inhibitor which reduces the reabsorption of glucose from kidney
- What is Ardance 10 mg Tablet used for?: Improving glycemic control in adults
- Pregnancy warnings: Unsafe to use during pregnancy
- Breast-feeding warnings: Probably unsafe to use during breastfeeding
- Effect on kidney function: Use cautiously in patients with underlying kidney disease
- Effect on liver function: No dose adjustment needed for mild to moderate liver disease
- Quick Tips:
- Used alone or with other diabetes medicines to control blood sugar
- May cause dehydration or increased urination - stay hydrated
- May cause hypoglycemia if used with other antidiabetic medicines or alcohol
- Can cause genital fungal and/or urinary tract infections - practice good hygiene
- Monitor blood sugar regularly while taking
- Inform doctor if experiencing specific symptoms