Ardance 25 mg (Tablet)
Unit Price: ৳ 50.00 (3 x 10: ৳ 1,500.00)
Strip Price: ৳ 500.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Empagliflozin |
| Company | Pharmacil limited |
| Also available as |
Indications
- Adjunct to diet and exercise for type 2 diabetes mellitus
- Reduction of cardiovascular death in adults with type 2 diabetes and established cardiovascular disease
Pharmacology
SGLT-2 inhibitor
Dosage & Administration
- Recommended dose of 10 mg once daily
- May be increased to 25 mg once daily
- Can be taken with or without food
Interactions
- Increased urine volume with diuretics
- Increased risk of hypoglycemia with insulin or insulin secretagogues
- Positive urine glucose test due to increased urinary glucose excretion
- Unreliable 1,5-AG assay results in patients taking SGLT2 inhibitors
Contraindications
- History of serious hypersensitivity reaction to Empagliflozin
- Severe renal impairment
- End-stage renal disease
- Dialysis
Side Effects
- Urinary tract infections
- Female genital mycotic infections
- Dehydration
- Hypotension
- Weakness
- Dizziness
- Increased thirstiness
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnancy
- Use during pregnancy if potential benefit justifies potential risk to fetus
- Not recommended during breastfeeding
Precautions & Warnings
- Assessment of renal function prior to initiation
- Not to be initiated in patients with eGFR less than 45 ml/min/1.73 m2
Overdose Effects
Supportive measures recommended
Therapeutic Class
Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors
Storage Conditions
Keep below 30°C, protected from light & moisture, out of reach of children
Chemical Structure
- Molecular Formula: C23H27ClO7
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-1275-empagliflozin-chemical-structure-Z3X0mrA6UvgM682Jgp8K.svg
Common Questions
- Ardance 25 mg Tablet is a SGLT-2 inhibitor for reducing glucose reabsorption from kidney
- Commonly used to improve glycemic control in adults
- May be unsafe to use during pregnancy
- Probably unsafe to use during breastfeeding
- Should be used cautiously in patients with underlying kidney disease
- No dose adjustment needed for patients with mild to moderate liver disease