Tufcon 200 mg (Tablet)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Tolfenamic acid
Company Concord pharmaceuticals ltd

Title

Tufcon 200 mg Tablet

Categories

  • Pain Relief
  • Analgesic
  • Migraine Relief
  • NSAIDs

Description

Tufcon 200 mg Tablet is a potent inhibitor of cyclooxygenase enzyme, thus it inhibits the synthesis of important inflammatory mediators such as thromboxane (TX) B2 and prostaglandin (PG) E2. It is used for relieving the pain of migraine headache, post-operative pain, and fever. It is contraindicated in cases of active gastrointestinal bleeding, active gastrointestinal ulceration, severe heart failure, and not recommended for use during the third trimester of pregnancy.

Dosage

  • Adult: 200 mg for acute migraine attacks, 100-200 mg for mild to moderate pain
  • Should be taken with food
  • Pediatric dosage regimen not established

Pharmacology

  • Belongs to the fenamate group
  • Potent inhibitor of cyclooxygenase enzyme
  • Inhibits the synthesis of inflammatory mediators
  • Absorbed from GI tract with 85% bioavailability
  • Metabolized in the liver, excreted in urine and feces

Interaction

  • Increases absorption with Metoclopramide and Magnesium hydroxide
  • Decreases absorption with Aluminium hydroxide
  • Increases risk of bleeding with anticoagulants and other NSAIDs
  • Affects antihypertensive response to certain medications

Contraindications

  • Active gastrointestinal bleeding
  • Active gastrointestinal ulceration
  • Severe heart failure
  • History of gastrointestinal bleeding related to previous NSAID therapy

Side Effects

  • Rare alveolitis
  • Hepatic damage
  • Pancreatitis
  • Stevens-johnson syndrome
  • Blood disorder
  • Visual disturbances
  • Gastrointestinal bleeding
  • Nausea
  • Vomiting
  • Headache
  • Drowsiness
  • Dizziness
  • Diarrhea

Pregnancy & Lactation

  • Not recommended during pregnancy unless essential
  • Not recommended during the third trimester of pregnancy
  • NSAIDs can appear in breast milk in very low concentrations

Precautions & Warnings

  • Needed for patients with asthma, bleeding disorders, cardiovascular diseases, peptic ulceration, hypertension, liver infection, cardiac or renal function impairment, and elderly
  • Increase water intake or dose reduction to reduce dysuria

Overdose Effects

  • Headache
  • Nausea
  • Vomiting
  • Gastrointestinal bleeding
  • Diarrhea
  • Dizziness
  • Convulsions
  • Acute renal failure
  • Liver damage

Therapeutic Class

  • Rheumatoid Arthritis Drugs
  • NSAIDs
  • Migraine Drugs

Storage Conditions

Store in a cool and dry place, away from light, keep out of the reach of children

Chemical Structure

  • Molecular Formula: C14H12ClNO2
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-1092-tolfenamic-acid-chemical-structure-dzPweN5r9IE4mD1xFrIL.svg

Common Questions

  • Question:
    • What is Tufcon 200 mg Tablet?
    • What are the uses of Tufcon 200 mg Tablet?
  • Answer:
    • Tufcon 200 mg Tablet is a potent inhibitor of cyclooxygenase enzyme.
    • Used for the treatment of acute migraine attacks and mild to moderate pain.

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