Tossnil 200 mg (Tablet)
Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tolfenamic acid |
| Company | Mystic pharmaceuticals ltd |
Title
- Tossnil 200 mg Tablet
Categories
- Medicine
- Pain Relief
- Analgesic
Description
- Potent inhibitor of cyclooxygenase enzyme
- Relieves the pain of migraine headache
- Used as an analgesic in post-operative pain and fever
- Inhibits prostaglandin synthesis
- Direct antagonistic action on prostaglandin receptors
- Absorbed from gastrointestinal tract
- Peak plasma concentration in 60-90 minutes
- Bioavailability of 85%
- Protein-binding of 99%
- Plasma half-life of 2 hours
- Metabolized in the liver
- Excreted in urine and feces
- Increases rate of absorption with Metoclopramide
- Decreases rate of absorption with Aluminium hydroxide
- Increases plasma concentration of Lithium Methotrexate
- Interacts with anticoagulants and other NSAIDs
- Co-administration affects loop diuretics, B-blockers, ACE Inhibitors
- Can lead to increased risk of nephrotoxicity with certain drugs
- Avoid in cases of active gastrointestinal bleeding or ulceration
- Not recommended during the third trimester of pregnancy
- Not recommended during breastfeeding
- Precaution needed in patients with asthma, bleeding disorders, cardiovascular diseases
- Precaution needed in patients with peptic ulceration, hypertension, liver infection
- Precaution needed in patients with cardiac or renal function impairment, elderly
- Symptoms of overdose include headache, nausea, vomiting, gastrointestinal bleeding
- Symptoms of overdose include drowsiness, dizziness, convulsions
- Store in a cool, dry place away from light
- Chemical structure: C14H12ClNO2