Dermazole Bar 2% (Medicated Bar)

75 gm bar: ৳ 600.00

Medicine Details

Category Details
Generic Ketoconazole
Company Derma health care

Title

Dermazole Bar 2% Medicated Bar

Categories

  • Medicine
  • Antifungal

Description

Dermazole Bar 2% is indicated for the treatment and prophylaxis of various fungal infections such as pityriasis versicolor, seborrhoeic dermatitis, dandruff, tinea corporis, tinea cruris, tinea manus, athlete's foot, cutaneous candidosis, candidal intertrigo, tinea versicolor, seborrhoeic dermatitis, oral thrush, vaginal candidiasis, systemic candidiasis, paracoccidioidomycosis, and more.

Dimensions

  • Not provided

Color options

  • None

Functions

  • Treats and prevents fungal infections
  • Prophylactic treatment
  • Maintenance treatment

Materials

  • Active ingredient: Ketoconazole

Technical specifications

  • Molecular Formula: C26H28Cl2N4O4
  • Chemical Structure: Image available

Design elements

  • Bar shape

Usability features

  • Contraindicated in patients with known hypersensitivity to ketoconazole

Pharmacology

  • Interacts with 14-α-sterol demethylase
  • Inhibits ergosterol synthesis
  • Increases fungal cellular permeability

Dosage and administration

  • Shampoo: Apply to affected areas, leave for 3-5 minutes before rinsing
  • Cream: Apply to affected areas once or twice daily
  • Tablet: Dosage varies based on specific indication

Interaction

  • Interacts with antimuscarinics, antacids, H2-blockers, PPIs, sucralfate, rifampicin, isoniazid, efavirenz, nevirapine, phenytoin, oral contraceptives, CYP3A4 substrates

Contraindications

  • Hypersensitivity to ketoconazole

Side effects

  • Shampoo: Local burning sensation, itching, contact dermatitis
  • Cream: Burning sensation, erythema, pruritus, application site bleeding, dryness
  • Tablet: Nausea, itching, idiosyncratic liver reaction

Pregnancy and lactation

  • Shampoo: Not absorbed through the skin
  • Cream: Limited data available, animal studies show no adverse effects
  • Tablet: Category C, not recommended during pregnancy and lactation

Precautions and warnings

  • Shampoo: Gradual withdrawal of steroid therapy advised
  • Cream: Not for ophthalmic use, recovery period after corticosteroid use
  • Tablet: Monitor liver enzyme levels in patients with previous liver disease

Overdose effects

  • Shampoo: Not expected for external use
  • Cream: Exaggerated application may lead to erythema, oedema, burning sensation

Therapeutic class

  • Drugs for subcutaneous and mycoses

Storage conditions

  • Below 25°C, away from light and moisture

Commonly asked questions

  • What is Dermazole Bar 2% Medicated Bar? - Belongs to the class of drugs called azole antifungals.
  • What is Dermazole Bar 2% Medicated Bar used for? - Treats a number of fungal infections.

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