Janmet XR 50 mg+500 mg (Tablet (Extended Release))

Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)

Strip Price: ৳ 200.00

Medicine Details

Category	Details
Generic	Sitagliptin metformin hydrochloride
Company	Acme laboratories ltd
Also available as	Janmet 50 mg tablet Janmet 50 mg tablet

Indications

Adjunct to diet and exercise for type 2 diabetes mellitus
Improving glycemic control in adults
Limitations of use in type 1 diabetes
Limitations of use in diabetic ketoacidosis
Not studied in patients with a history of pancreatitis

Pharmacology

Combines sitagliptin and metformin
Antihyperglycemic agents
Complementary mechanisms of action
DPP-4 inhibitor
Biguanide class

Dosage & Administration

Individualized dosage
Maximum recommended daily dose
Twice daily with meals
Gradual dose escalation
Starting dose based on patient's current regimen

Interaction

Cationic drugs caution
Phenprocoumon interaction
Levothyroxine interaction

Contraindications

Renal disease or dysfunction
Metabolic acidosis
Hypersensitivity reaction
Contrast materials interaction

Side Effects

Common adverse reactions
Hypoglycemia
Nasopharyngitis
Diarrhea
Headache

Pregnancy & Lactation

Pregnancy Category B
No adequate studies in pregnant women
Caution in nursing women

Precautions & Warnings

Lactic Acidosis risk factors
Thyroid-stimulating hormone monitoring
Vitamin B12 level monitoring
Hepatic disease caution
Renal function assessment
Acute pancreatitis risk
Hematologic parameter monitoring
Allergic and hypersensitivity reactions
Macrovascular risk reduction

Overdose Effects

Supportive measures for sitagliptin overdose
Dialyzable nature of sitagliptin
Supportive therapy for metformin overdose
Dialyzable nature of metformin
Pancreatitis risk in metformin overdose

Therapeutic Class

Oral hypoglycemic preparations

Storage Conditions

Store below 25°C
Dry place away from light
Keep out of reach of children
Do not use after expiry date
Dispensed only on prescription

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