Ozempic 1.34 mg/ml (SC Injection)
1.5 ml cartridge with device: ৳ 14,259.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Semaglutide |
| Company | Novo nordisk pharma pvt ltd |
Indications
- Adjunct to diet and exercise for type 2 diabetes mellitus
- Reduction of risk of cardiovascular events in diabetes patients
- Weight management for patients with obesity
- Weight management for patients with overweight and comorbid conditions
Pharmacology
- GLP-1 receptor agonist
- Stimulation of insulin secretion
- Lowering of glucagon secretion
- Reduction of blood glucose in a glucose-dependent manner
- Reduction of appetite
Dosage & Administration
- Tablet formulation available
- Injection formulation available
- Tablet to be taken at least 30 minutes before first food or beverage
- Different starter doses for diabetes and obesity
- Weekly injection administration for both indications
- Subcutaneous injection in abdomen, thigh, or upper arm
- Site change without dose adjustment
Interaction
- Potential impact on absorption of concomitant oral medications
- Caution with oral medications requiring rapid absorption
Contraindications
- Hypersensitivity to active substance or excipients
Side Effects
- Possible hypoglycemia when used with insulin or sulfonylurea
- Common adverse reactions: gastrointestinal disorders, nausea, diarrhea, vomiting, abdominal pain, constipation
- Mild to moderate severity and short duration
- Potential allergic reactions, injection site reactions, lipodystrophy, pruritus, rash
Pregnancy & Lactation
- Contraindicated during pregnancy
- Discontinue at least 2 months before planned pregnancy
- Avoid during breastfeeding
Precautions & Warnings
- Not for use in type 1 diabetes or treatment of diabetic ketoacidosis
- Prompt discontinuation if pancreatitis suspected
- Monitoring for diabetic retinopathy in patients with the condition
Use in Special Populations
- Safety and efficacy not established in children and adolescents below 18 years
- No dose adjustment required based on age or renal impairment
- Caution in hepatic impairment
Overdose Effects
- Reported overdose up to 4 mg in single dose and in a week
- Commonly reported adverse reaction: nausea
- No specific antidote
- Supportive treatment based on clinical symptoms
- Consideration of dose adjustment when used with other antidiabetic medications
- Guidelines for missed doses
Therapeutic Class
- GLP-1 receptor agonists
Storage Conditions
- Refrigeration at 2°C to 8°C
- Avoid freezing
- Keep out of reach of children