Furabac 100 mg (Capsule (Sustained Release))

Title

• Furabac

Categories

• Urinary Tract Infection (UTI) Treatment
• Antibacterial Agent
• Urinary Anti-infective

Description

• Furabac is specifically indicated for the treatment & prophylaxis of urinary tract infections caused by susceptible strains of Escherichia coli, Enterococci, Staphylococcus aureus, Staphylococcus saprophyticus and certain susceptible strains of Klebsiella and Enterobacter species.

Dosage

• Nitrofurantoin tablet (In adults): Uncomplicated urinary tract infections: 50-100 mg four times a day
• Long-term suppressive therapy: 50-100 mg at bedtime may be adequate
• Nitrofurantoin capsule (In adults): Acute Uncomplicated Urinary Tract Infections (UTIs): 50 mg four times daily for 7 days
• Long term suppression: 50-100 mg once a day
• Prophylaxis: 50 mg four times daily for the duration of procedure and for three days thereafter
• Nitrofurantoin SR capsule: One 100 mg capsule every 12 hours for seven days
• Genito-urinary surgical prophylaxis: One capsule twice daily on day of procedure and for next 3 days
• Nitrofurantoin suspension: Children: 5-7 mg/kg/day in four divided doses

Mode of Action

• Highly soluble in urine, may impart a brown color
• Inactivates or alters bacterial ribosomal proteins and other macromolecules
• Active against various bacteria including Escherichia coli, Staphylococcus saprophyticus, Enterococcus faecalis, Staphylococcus aureus, Klebsiella oxytoca

Administration

• Nitrofurantoin should be taken with food.

Interactions

• Antacids containing Magnesium Trisilicate reduces absorption of Furabac
• Uricosuric drugs, such as Probenecid and Sulfinpyrazone, can inhibit renal tubular secretion of Furabac

Contraindications

• Anuria, oliguria or significant impairment of renal function
• Pregnant patients at 38-42 weeks, during labor and delivery
• Known hypersensitivity to Nitrofurantoin

Side Effects

• Nausea
• Headache
• Flatulence
• Diarrhea
• Dyspepsia
• Abdominal pain
• Constipation
• Emesis
• Dizziness
• Drowsiness

Pregnancy & Lactation

• Pregnancy Category B
• No adequate and well-controlled studies in pregnant women
• Nitrofurantoin detected in human breast milk in trace amounts

Precautions & Warnings

• Discontinue if acute, sub-acute or chronic pulmonary reactions occur
• Avoid taking antacid preparations containing magnesium trisilicate

Overdose Effects

• Occasional incidents of acute overdosage of Furabac have not resulted in any specific symptoms other than vomiting

Therapeutic Class

• Systemic Urinary Anti-infective

Storage Conditions

• Do not store above 30°C
• Keep away from light and out of the reach of children

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• Uritro 25 mg/5 ml (Oral Suspension) - team-pharmaceuticals-ltd