Voriaid 50 mg (Tablet)
Unit Price: ৳ 50.00 (1 x 10: ৳ 500.00)
Strip Price: ৳ 500.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Voriconazole |
| Company | Labaid pharma ltd |
| Also available as |
Indications
- Treatment of invasive aspergillosis
- Treatment of candidemia in nonneutropenic patients
- Treatment of disseminated candidiasis in skin, abdomen, kidney, bladder wall, and wounds
- Treatment of esophageal candidiasis
- Treatment of serious infections caused by Scedosporium apiospermum and Fusarium Species
- Treatment for patients intolerant of or refractory to other therapy
Pharmacology
- Voriconazole is a triazole antifungal medication
- Binds and inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-alpha sterol demethylase
- Results in depletion of ergosterol in fungal cell membrane
Dosage & Administration
- Oral administration at least one hour before or one hour following a meal
- Different loading and maintenance dose regimens based on body weight
- Injection dosage regimen for specific infections
Interaction
- Adjust Voriaid dosage with CYP3A4, CYP2C9, and CYP2C19 inhibitors and inducers
- Monitoring for adverse reactions or lack of efficacy with certain drug co-administrations
- Increase maintenance oral and intravenous dosage with co-administration of Phenytoin or Efavirenz
Contraindications
- Known hypersensitivity to Voriconazole or any other components of the drug
- Co-administration contraindications with specific drugs
Side Effects
- Abdominal pain
- Anemia
- Blurred vision
- Headache
- Chest pain
- Nausea
- Diarrhea
Pregnancy & Lactation
- Use during pregnancy only if the potential benefit justifies the potential risk to the fetus
Precautions & Warnings
- Long term exposure requires careful assessment of benefit-risk balance
- Reported association with squamous cell carcinoma of the skin with long-term treatment
Use in Special Populations
- Efficacy not established in children under 12 years of age
Overdose Effects
- No available data on overdose effects
Therapeutic Class
- Other Antifungal preparations
Reconstitution
- Instructions for reconstituting suspension
Storage Conditions
- Keep out of reach of children
- Store in a dry place below 25°C
- Store Voriaid powder for suspension between 2°C to 8°C