Indaren-G 110 mcg+50 mcg (Inhalation Capsule)
Unit Price: ৳ 70.00 (3 x 10: ৳ 2,100.00)
Strip Price: ৳ 700.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Indacaterol glycopyrronium |
| Company | Renata limited |
Therapeutic Class
- Combined bronchodilators
Indications
- Long-term once-daily maintenance bronchodilator treatment
- Airflow obstruction in patients with chronic obstructive pulmonary disease (COPD)
- Chronic bronchitis
- Emphysema
Composition
- Indacaterol 110 mcg as Indacaterol Maleate INN (Micronized)
- Glycopyrronium 50 mcg as Glycopyrronium Bromide BP (Micronized)
Pharmacology
- Inhalation powder drug
- Delivery of a combination of Glycopyrronium and Indacaterol by oral inhalation
- Pharmacologic effects of beta2-adrenoceptor agonist drugs
- Stimulation of intracellular adenyl cyclase
- Increased cyclic AMP levels causing relaxation of bronchial smooth muscle
Dosage & Administration
- For adults (18 years or older)
- Oral inhalation only
- Maintenance treatment of COPD: 1 inhalation once daily
- Use at the same time every day, not more than 1 time every 24 hours
- Geriatric use at the recommended dose
- Not indicated for use in children and adolescents
- Safe for patients with mild to moderate renal impairment
- Safe for patients with mild to moderate hepatic impairment
Interaction
- No specific interaction studies conducted for the combination
- Concomitant use with β-adrenergic blockers, anticholinergics, or sympathomimetic agents not recommended
- Caution required with concomitant use of hypokalemic treatment
Contraindications
- Hypersensitivity to Glycopyrronium or Indacaterol
- Severe hypersensitivity to milk proteins
- Contraindicated in patients with asthma without use of a long-term asthma control medication
Side Effects
- Cardiovascular effects
- Ocular disorders
- Urinary retention
- Gastrointestinal disorders
- Dry mouth
- Cough
- Immediate hypersensitivity reactions
- Hypokalemia
- Hyperglycemia
- Headache
- Nervousness
- Insomnia
- Muscle spasms
- Fatigue
- Malaise
Pregnancy & Lactation
- Pregnancy category C
- Use during pregnancy justified if expected benefit to the patient outweighs potential risk to the fetus
- Consideration for use in breast-feeding women if expected benefit to the woman is greater than any possible risk to the infant
Precautions & Warnings
- Increases the risk of serious asthma-related events
- Not to be used in acutely deteriorating COPD or asthma
- Use with caution in patients with cardiovascular disorders
- Use with caution in patients with convulsive disorders, thyrotoxicosis, diabetes mellitus, and ketoacidosis
- Worsening of narrow-angle glaucoma may occur
- Worsening of urinary retention may occur
- Alert to hypokalemia and hyperglycemia
Overdose Effects
- Information not available on clinically relevant overdosing
- Overdose could lead to exaggerated effects of β2-adrenergic stimulants or induce anticholinergic effects
- Supportive and symptomatic treatment indicated
Storage Conditions
- Avoid storage in direct sunlight or heat
- Store in a cool & dry place
- Keep away from eyes
- Keep all medicines out of reach of children