Pregaben CR 82.5 mg (Tablet (Controlled Release))

Unit Price: ৳ 25.00 (3 x 10: ৳ 750.00)
Strip Price: ৳ 250.00

Medicine Details

Title

  • Pregaben CR 82.5 mg Tablet

Categories

  • Medicine
  • Pharmaceuticals
  • Neuropathic Pain Management
  • Seizure Treatment
  • Fibromyalgia Therapy

Description

  • Pregaben CR 82.5 mg Tablet is an anticonvulsant
  • First-line treatment for neuropathic pain, shingles, seizures, and fibromyalgia
  • Route of administration: Oral, with or without food
  • Must be swallowed whole and should not be split, crushed or chewed
  • Should be administered after an evening meal
  • Should not be discontinued abruptly

Dosage

  • Recommended dosage for different conditions
  • Maximum recommended doses for adults
  • Dosing adjustments based on efficacy and tolerability

Mode of Action

  • Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
  • Binds with high affinity to the alpha2-delta site in central nervous system tissues
  • Mechanism of action not fully elucidated

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Contraindications

  • Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components

Interaction

  • Unlikely to be involved in significant pharmacokinetic drug interactions
  • No significant interactions with food or others

Side Effects

  • Common side effects in adults: dizziness, somnolence, dry mouth, edema, blurred vision, weight gain, thinking abnormal
  • Common side effects in pediatric patients: increased weight, increased appetite

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Small amounts detected in the milk of lactating women
  • Breastfeeding not recommended due to potential risk of tumorigenicity

Precautions & Warnings

  • Angioedema can occur and may be life-threatening, discontinue immediately
  • Discontinue immediately if hypersensitivity reactions occur
  • Increased risk of suicidal thoughts or behavior
  • Respiratory depression may occur when used with concomitant CNS depressants

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients for various conditions

Overdose Effects

  • Signs and symptoms of overdose
  • No specific antidote
  • General supportive care indicated

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage Conditions

  • Keep in a cool & dry place (below 30°C)
  • Protected from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular formula: C8H17NO2
  • Chemical Structure: Image available

Commonly Asked Questions

  • Information about Pregaben CR 82.5 mg Tablet
  • Frequency, storage, and disposal instructions
  • Dosage frequency
  • Use with other medications
  • Potential weight gain
  • Quick tips for usage

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