Levamdocal 5 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Levamlodipine maleate |
| Company | Beximco pharmaceuticals ltd |
| Also available as | Levamdocal 125 mg tabletLevamdocal 25 mg tablet |
Title
- Levamdocal
Categories
- Medicine
- Healthcare
- Therapeutic
Description
- Calcium channel blocker for the treatment of hypertension
- May be used alone or in combination with other antihypertensive agents
- Lowers blood pressure to reduce the risk of cardiovascular events
Dosage Form
- Tablet
Dosage Strengths
- 2.5mg
- 5mg
Age Group
- Adults
- Elderly
- Pediatric patients (6 years and older)
Route of Administration
- Oral
Absorption Time
- 6-12 hours
Bioavailability
- 64-90%
Metabolism
- Primarily mediated by CYP3A4
Excretion
- 60% eliminated in urine
- 10% eliminated as the unmetabolized drug
Dosage for Adults
- 2.5mg-5mg once daily
Dosage for Elderly
- 1.25mg once daily
Pediatric Dosage
- 1.25mg-2.5mg once daily
CYP3A Inhibitors
- May require dose reduction when co-administered
CYP3A Inducers
- Quantitative effects not available
Simvastatin Interaction
- Limit the dose to 20mg daily when co-administered with amlodipine
Immunosuppressants Interaction
- May increase systemic exposure of cyclosporine or tacrolimus
Food Interaction
- Can be taken with or without food
- Avoid grapefruit products & natural licorice
Contraindications
- Known sensitivity to amlodipine
Common Side Effects
- Difficulty in breathing
- Dizziness
- Reflex Tachycardia
- Hypotension
- Abdominal Pain
- Edema
Rare Side Effects
- Diarrhea
- Back pain
- Headache
- Fatigue
- Nausea
Pregnancy & Lactation
- Limited data available
- No adverse effects on breastfed infant observed
Precautions
- Symptomatic hypotension is possible
- Increased Angina or Myocardial Infarction
- Titrate slowly in patients with hepatic failure
Overdose Effects
- Excessive peripheral vasodilation
- Marked hypotension
- Possibly reflex tachycardia
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Cool & dry place
- Protect from light & moisture
- Keep out of reach of children