Inbuten 200 mg (Capsule)
Unit Price: ৳ 70.00 (2 x 7: ৳ 980.00)
Strip Price: ৳ 490.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftibuten dihydrate |
| Company | Pharmacil limited |
| Also available as |
Indications
- Acute Bacterial Exacerbations of Chronic Bronchitis
- Acute Bacterial Otitis Media
- Pharyngitis and Tonsillitis
Pharmacology
Ceftibuten is a semi-synthetic Cephalosporin antibiotic for oral administration.
Dosage & Administration
- Otitis Media:
- Adult Dosage: 400 mg orally every 24 hours for 10 days
- Pediatric Dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days
- Tonsillitis/Pharyngitis:
- Adult Dosage: 400 mg orally every 24 hours for 10 days
- Pediatric Dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days
- Bronchitis:
- Adult Dosage: 400 mg orally every 24 hours for 10 days
- Pediatric Dosage: >12 years: 400 mg orally every 24 hours for 10 days
- Cystitis:
- Adult Dosage: 400 mg orally every 24 hours for 7 days
- Pediatric Dosage: >12 years: 400 mg orally every 24 hours for 7 days
- Pneumonia:
- Adult Dosage: 200 mg orally every 12 hours for 7 to 14 days
- Pediatric Dosage: >12 years: 200 mg orally every 12 hours for 7 to 14 days
- Sinusitis:
- Adult Dosage: 400 mg orally every 24 hours for 10 to 14 days
- Pediatric Dosage: >12 years: 400 mg orally every 24 hours for 10 to 14 days
- Urinary tract Infection:
- Adult Dosage: 400 mg orally every 24 hours for 10 days
- Pediatric Dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days
Interaction
Theophylline & Antacid do not alter the pharmacokinetic profile of Inbuten. Ranitidine increases the Cmax & AUC of Inbuten.
Contraindications
Ceftibuten is contraindicated in patients with known allergy to the cephalosporin group of antibiotics.
Side Effects
- Nausea
- headache
- diarrhea
- dyspepsia
- dizziness
- abdominal pain
- vomiting
Pregnancy & Lactation
Pregnancy Category B. Ceftibuten should be used in pregnancy only when the benefit clearly outweighs the risk.
Precautions & Warnings
Prolonged treatment may result in the possible emergence and overgrowth of resistant organisms. Careful observation of the patient is essential.
Use in Special Populations
- Renal Impairment:
- CrCl 5 to 29 ml/min: 2.25 mg/kg or 100 mg orally once a day
- CrCl 30 to 49 ml/min: 4.5 mg/kg or 200 mg orally once a day
- Hepatic Impairment: Dose adjustment is not necessary.
Therapeutic Class
Third generation Cephalosporins
Reconstitution
- The small bottle contains purified water and large bottle contains granules
- Prepared suspension to be consumed within 14 days of preparation if kept in a refrigerator.
Storage Conditions
Store below 25°C, protected from light and moisture. For Suspension: After reconstitution, the suspension may be used for 14 days while stored at 2° to 8°C.