Muslofen 10 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Baclofen |
| Company | Novatek pharmaceuticals ltd |
Indications
- spasticity resulting from multiple sclerosis
- flexor spasms and concomitant pain
- clonus and muscular rigidity
- skeletal muscle spasm resulting from rheumatic disorders
- spinal cord injuries and other spinal cord diseases
- cerebrovascular accidents or neoplastic or degenerative brain disease
Pharmacology
- Inhibits monosynaptic and polysynaptic reflexes
- Stimulates GABA receptors
- Inhibits release of glutamate and aspartate
- Produces CNS depression
- Exerts antinociceptive effect
Dosage & Administration
- Dosage for adults & children over 10 years
- Dosage for children under 10 years
- Maximum daily dosage
- Gradual dosage increase for adults
- Gradual dosage increase for children
Interaction
- Increased sedation with central nervous system agents
- Risk of respiratory depression
- Increased fall in blood pressure with antihypertensives
- Potentiation of pharmacological effects with tricyclic antidepressants
- Reports of mental confusion and agitation with Parkinson’s medication
- CNS depressant effects with MAO inhibitors
- Synergistic effect with magnesium sulphate or other neuromuscular blocking agents
Contraindications
- Hypersensitivity to any component of the product
Side Effects
- Transient drowsiness
- Daytime sedation
- Dizziness
- Weakness
- Fatigue
- Headache
- Insomnia
- Euphoria
- Depression
- Visual disturbances
- Hypotension
- Gastrointestinal discomfort
- Urinary frequency
- Rash
- Respiratory depression
Pregnancy & Lactation
- Pregnancy category B3
- Excretion in breast milk
- Administered to pregnant women only if benefits outweigh hazards
Precautions & Warnings
- Lower doses for patients with impaired renal function
- Cautious treatment for patients with psychotic disorders
- Potential lowering of convulsion threshold in patients with epilepsy
- Use with caution in patients with peptic ulcers, cerebrovascular diseases, or hepatic, renal or respiratory failure
- Careful monitoring of respiratory and cardiovascular function
- Neurogenic bladder disturbances
- Poor tolerance in patients with stroke
- Appropriate laboratory tests in patients with hepatic diseases or diabetes mellitus
Overdose Effects
- Importance of gastric lavage in case of severe overdose
Therapeutic Class
- Centrally acting Skeletal Muscle Relaxants
Storage Conditions
- Keep below 30°C temperature
- Keep away from light & moisture
- Keep out of the reach of children