X-tol 200 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tolfenamic acid |
| Company | Novatek pharmaceuticals ltd |
Title
- X-tol 200 mg Tablet
Categories
- Medicine
- Pain Relief
- Analgesic
- Migraine Treatment
- NSAIDs
- Pharmacology
Dosage and administration
- 200 mg for acute migraine attacks
- 100-200 mg for mild to moderate pain
- Should be taken with food
- Dose adjustments for renal impairment
Indications
- Relieving migraine headache
- Analgesic for post-operative pain and fever
Pharmacology
- Inhibitor of cyclooxygenase enzyme
- Inhibits synthesis of inflammatory mediators
- Direct antagonistic action on prostaglandin receptors
- Readily absorbed from GI tract
- Peak plasma concentration in 60-90 minutes
- Metabolized in the liver
Interaction
- Increased absorption with Metoclopramide and Magnesium hydroxide
- Decreased absorption with Aluminium hydroxide
- Risks of bleeding with anticoagulants and other NSAIDs
- Decreased antihypertensive response to loop diuretics and ACE Inhibitors
- Increased plasma concentration of Lithium, Methotrexate, and cardiac glycosides
- Increased risk of nephrotoxicity with ACE inhibitors, Ciclosporin, Tacrolimus, or diuretics
Contraindications
- Active gastrointestinal bleeding or ulceration
- Severe heart failure
- History of gastrointestinal bleeding or haemorrhage related to previous NSAID therapy
- History of gastrointestinal perforation related to previous NSAID therapy
Side effects
- Rare alveolitis
- Hepatic damage
- Pancreatitis
- Pulmonary eosinophilia
- Stevens-johnson syndrome
- Angioedema
- Blood disorder
- Depression
- Diarrhea
- Dizziness
- Drowsiness
- Dysuria
- Euphoria
- Gastrointestinal bleeding
- Hallucination
- Insomnia
- Malaise
- Nausea
- Hearing disturbances
- Rash
- Visual disturbances
- Vertigo
- Raised blood pressure
- Symptoms of overdose include headache, vomiting, and gastrointestinal bleeding
Pregnancy and lactation
- Not recommended during pregnancy unless considered essential by a doctor
- Avoid during the third trimester of pregnancy
- NSAIDs can appear in breast milk in low concentrations
Precautions and warnings
- Needed for patients with asthma, bronchospasm, bleeding disorders, cardiovascular diseases, peptic ulceration, hypertension, liver or renal function impairment, and elderly
- Increase water intake or dose reduction to reduce dysuria
Overdose effects
- Symptoms include headache, nausea, vomiting, gastrointestinal bleeding, and drowsiness
- Acute renal failure and liver damage are possible in significant poisoning cases
Therapeutic class
- Rheumatoid Arthritis Drugs
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
- Migraine Treatment Drugs
Storage conditions
- Store in a cool and dry place
- Keep away from light
- Keep out of the reach of children
Chemical structure
- Molecular Formula: C14H12ClNO2
Commonly asked questions
- What is X-tol 200 mg Tablet? - It is a potent inhibitor of cyclooxygenase enzyme
- What are the uses of X-tol 200 mg Tablet? - Treatment of acute migraine attacks and mild to moderate pain
- Quick tips - Take with food, avoid long-term use to prevent complications, inform doctor in specific medical situations