Oritam 250 mg (Tablet)

Unit Price: ৳ 16.00 (3 x 10: ৳ 480.00)
Strip Price: ৳ 160.00

Medicine Details

Category Details
Generic Levetiracetam
Company Orion pharma ltd
Also available as
Oritam 500 mg tablet Oritam 500 mg oral solution

Indications

  • Treatment of partial-onset seizures
  • Treatment of myoclonic seizures
  • Treatment of primary generalized tonic-clonic seizures

Description

  • Mechanism of antiepileptic effect is unknown
  • Minimal activity in submaximal stimulation
  • Inhibition of burst firing
  • Prevents hyper synchronization of epileptiform burst firing
  • Prevents propagation of seizure activity

Dosage

  • Recommended starting dose for adults and adolescents
  • Maximum dose for adults and adolescents
  • Use of tablet formulation in pediatric population

Administration

  • Oral administration
  • Taken with sufficient quantity of liquid
  • Can be taken with or without food
  • Daily dose is administered in two equally divided doses

Interaction

  • No influence on serum concentrations of existing antiepileptic medicinal products
  • Inhibition of renal clearance of primary metabolite by probenecid
  • Decrease in methotrexate clearance
  • Reports of decreased efficacy when concomitantly administered with osmotic laxative macrogol
  • No alteration in absorption by food

Contraindications

  • Hypersensitivity to the active substance or other pyrrolidone derivatives

Side Effects

  • Most common adverse reactions in adult patients
  • Most common adverse reactions in pediatric patients

Pregnancy & Lactation

  • Not recommended during pregnancy
  • Excreted in human breast milk
  • Breastfeeding not recommended

Precautions & Warnings

  • Dose adjustment in patients with renal impairment
  • Association with acute kidney injury
  • Rare cases of decreased blood cell counts
  • Risk of suicidal thoughts and behavior
  • No impact on growth and puberty in children

Use in Special Populations

  • Dose adjustment in elderly patients with compromised renal function
  • Daily dose adjustment according to renal function in renal impairment
  • No dose adjustment needed in patients with mild to moderate hepatic impairment
  • Dose reduction in severe hepatic impairment

Overdose Effects

  • Observation of somnolence, agitation, and respiratory depression
  • No specific antidote
  • Symptomatic treatment

Therapeutic Class

  • Adjunct anti-epileptic drugs

Storage Conditions

  • Store at a cool temperature and dry place, protected from light

Related Brands