Terbiderm 1% (Cream)
10 gm tube: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Terbinafine hydrochloride |
| Company | Orion pharma ltd |
| Also available as |
Indications
- Treatment of onychomycosis of the toenail or fingernail
- Tinea Capitis
- Fungal infection of the skin
- Yeast infections of the skin
- Pityriasis (tinea) versicolor
Pharmacology
- Inhibition of Ergosterol biosynthesis
- Inhibition of Squalene Epoxidase enzyme
- Fungicidal activity against Tricophyton Mentagrophyte and Trichophyton Rubrum
Dosage & Administration
- Tablet dosage for fingernail and toenail onychomycosis
- Granules dosage based on body weight
- Cream application duration for different skin conditions
- Spray application frequency and duration for different indications
Interaction
- Inhibitor of the CYP450 2D6 isozyme
- Potential interaction with specific drug classes
Contraindications
- Hypersensitivity to terbinafine
Side Effects
- Gastrointestinal symptoms
- Liver test abnormalities
- Rashes
- Urticaria
- Pruritus
- Taste disturbances
- Idiosyncratic and symptomatic hepatic injury
- Skin reactions
- Neutropenia
- Thrombocytopenia
- Angioedema
- Allergic reactions
Pregnancy & Lactation
- Not recommended during pregnancy
- Presence in breast milk
- Foetal toxicity and fertility studies in animals
Precautions & Warnings
- Rare cases of liver failure
- Serious skin reactions
- External use only
- Avoid contact with eyes
- Not recommended for patients with chronic or active liver disease
- Assessment of pre-existing liver disease before prescribing
Use in Special Populations
- Safety and efficacy not established in pediatric patients
- No evidence of different dosages or side-effects in elderly patients
Overdose Effects
- Limited clinical experience
- Symptoms including nausea, vomiting, abdominal pain, dizziness
Therapeutic Class
- Other Antifungal preparations
- Topical Antifungal preparations
Storage Conditions
- Store in a cool and dry place
- Below 30°C
- Protect from light