Clortha 15 mg (Tablet)
Unit Price: ৳ 4.00 (3 x 10: ৳ 120.00)
Strip Price: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Chlorthalidone |
| Company | Aci limited |
| Also available as | Clortha 25 mg tablet |
Indications
- Management of hypertension
- Adjunctive therapy in edema associated with congestive heart failure
- Adjunctive therapy in edema associated with hepatic cirrhosis
- Adjunctive therapy in edema associated with corticosteroid therapy
- Adjunctive therapy in edema associated with estrogen therapy
Pharmacology
- Thiazide-type diuretic-antihypertensive
- Treatment of hypertension
- Adjunctive therapy of edema associated with renal disease
- Adjunctive therapy of edema associated with stable patients with cirrhosis of the liver
- Inhibition of reabsorption of sodium and chloride in the distal renal tubule
- Promotion of water loss
- Long elimination half-life
Dosage & Administration
- Initiation of therapy with lowest possible dose
- Titration for maximum therapeutic benefit
- Single dose daily or every other day
- Usual adult dose of 25 to 50 mg daily for hypertension
- Usual dosage range of 12.5 to 50 mg daily for hypertension
- Lowest effective dose for edema of specific origin
- Adaptation of dosage for elderly patients
Interaction
- Caution in patients with impaired hepatic function
- Cautious dosage schedule in patients with severe coronary or cerebral atherosclerosis
- Potentiation of antihypertensive effects with diuretics
- Increase in likelihood of digitalis-induced cardiac arrhythmias
- Enhanced hypokalemic effects by corticosteroids
- Possible adjustment of insulin or oral antidiabetic agents dosage
Contraindications
- Anuria
- Severe renal failure
- Severe hepatic failure
- Refractory hypokalemia
- Enhanced potassium loss conditions
- Hypersensitivity to chlorthalidone and sulfonamide derivatives
Side Effects
- Hypokalemia
- Hyperuricemia
- Rise in blood lipids
- Hyponatremia
- Hypomagnesemia
- Hyperglycemia
- Hypochloremic alkalosis
Pregnancy & Lactation
- Avoidance of use in treating hypertension in pregnant women
- Avoidance of use for other indications in pregnancy, especially in first trimester
- Avoidance of use in nursing mothers
Precautions & Warnings
- Reduced dosage in moderate renal failure
- Avoidance in advanced renal failure
- Risk of precipitating hepatic encephalopathy in patients with liver cirrhosis
- Avoidance in pregnancy and lactation
Overdose Effects
- Nausea
- Weakness
- Dizziness
- Disturbances of electrolyte balance
Therapeutic Class
- Thiazide diuretics & related drugs
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children