Denbac 25 mg (Capsule)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Dantrolene sodium
Company Beacon pharmaceuticals plc
Also available as

Indications

  • Chronic Spasticity
  • Malignant Hyperthermia
  • Upper Motor Neuronal Disorders
  • Spinal Cord Injury
  • Stroke
  • Cerebral Palsy
  • Multiple Sclerosis

Pharmacology

  • Relaxation of Skeletal Muscles
  • Affects Excitation-Contraction Coupling
  • Interference with Ca++ Release

Dosage & Administration

  • Gradual Titration Schedule for Adults
  • Gradual Titration Schedule for Paediatric Patients
  • Preoperative Administration for Malignant Hyperthermia
  • Post Crisis Follow-up for Malignant Hyperthermia

Interaction

  • Potential Drowsiness
  • Concomitant Administration with CNS Depressants
  • Hepatotoxicity with Concomitant Estrogen Therapy

Contraindications

  • Active Hepatic Disease
  • Hepatitis
  • Cirrhosis

Side Effects

  • Drowsiness
  • Dizziness
  • Weakness
  • General Malaise
  • Fatigue
  • Diarrhea

Pregnancy & Lactation

  • Pregnancy Category C
  • Use Only if Potential Benefit Outweighs Risk
  • Avoid Usage in Nursing Mothers

Precautions & Warnings

  • Caution Against Driving or Hazardous Occupations
  • Caution with Concomitant Tranquilizing Agents
  • Possibility of Photosensitivity Reaction
  • Potential for Liver Damage
  • Liver Function Studies
  • Caution in Females
  • Caution in Patients over 35 Years
  • Caution in Patients with Impaired Pulmonary Function
  • Caution in Patients with Severely Impaired Cardiac Function
  • Caution in Patients with History of Liver Disease

Use in Special Populations

  • Long-term Safety in Paediatric Patients Not Established
  • Benefit-Risk Consideration in Pediatric Patients

Therapeutic Class

  • Centrally Acting Skeletal Muscle Relaxants

Storage Conditions

  • Cool & Dry Place
  • Protected from Light

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