Xerova EZ 20 mg+10 mg (Tablet)
Unit Price: ৳ 24.00 (4 x 7: ৳ 672.00)
Strip Price: ৳ 168.00
Medicine Details
Category | Details |
---|---|
Generic | Atorvastatin ezetimibe |
Company | Beacon pharmaceuticals plc |
Also available as |
Indications
- Reduction of elevated total cholesterol
- Reduction of low density lipoprotein cholesterol (LDL-C)
- Reduction of triglycerides (TG)
- Increase of high-density lipoprotein cholesterol (HDL-C)
- Adjunct to diet for hypercholesterolemia
- Adjunct treatment for homozygous familial hypercholesterolemia
Pharmacology
- Lowers plasma cholesterol
- Inhibits HMG-CoA reductase
- Reduces LDL production
- Inhibits absorption of cholesterol by small intestine
Dosage & Administration
- Recommended starting dose: 10/10 mg or 20/10 mg daily
- Dosage range: 10/10 mg to 80/20 mg daily
- Can be administered with or without food
- Dosage adjustment based on lipid levels
Interaction
- Risk of myopathy with concurrent administration of fibric acid derivatives
- Avoid coadministration with cyclosporine and gemfibrozil
- Enhanced risk of skeletal muscle effects with niacin
Contraindications
- Active liver disease
- Hypersensitivity to any component
Side Effects
- Rhabdomyolysis
- Myopathy
- Liver enzyme abnormalities
- Myalgia
- Abdominal pain
Pregnancy & Lactation
- Pregnancy Category X
- Contraindicated in pregnant women
- No benefit during pregnancy
- Unknown excretion in human milk
Precautions & Warnings
- Temporary withholding in conditions suggestive of myopathy
- Liver enzyme tests prior to initiating therapy
- Caution with drugs decreasing endogenous steroid hormones
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- No dosage adjustment in geriatric patients
Overdose Effects
- No specific recommended treatment
- Symptomatic and supportive measures
Therapeutic Class
- Other lipid regulating drugs
Storage Conditions
- Do not store above 30°C
- Keep in a dry place
- Protect from light
- Keep out of the reach of children