Xerova 40 mg (Tablet)

Unit Price: ৳ 28.00 (2 x 7: ৳ 392.00)
Strip Price: ৳ 196.00

Medicine Details

Category Details
Generic Atorvastatin calcium
Company Beacon pharmaceuticals plc
Also available as
Xerova 10 mg tablet Xerova 20 mg tablet

Indications

  • Adjunct to diet for reducing elevated total cholesterol levels
  • Adjunct to diet for reducing LDL cholesterol levels
  • Adjunct to diet for reducing apolipoprotein B levels
  • Adjunct to diet for reducing triglycerides levels

Pharmacology

  • Selective inhibitor of HMG-CoA reductase
  • Lowers plasma cholesterol and lipoprotein levels
  • Inhibits cholesterol synthesis in the liver
  • Increases hepatic LDL receptors for enhanced uptake of LDL

Dosage & Administration

  • Recommended starting dose for adults: 10 or 20 mg once daily
  • Maximum dose for adults: 80 mg once daily
  • Pediatric dose: 10-20 mg once daily for 10-18 years old
  • Dosage adjustment based on lipid levels within 2-4 weeks of initiation

Interaction

  • Increased risk of myopathy with concurrent administration of cyclosporine
  • Altered plasma concentrations with coadministration of antacid or colestipol
  • Increased plasma concentrations with coadministration of erythromycin or oral contraceptives
  • No clinically significant effect on prothrombin time with warfarin

Contraindications

  • Hypersensitivity to any component of the medication
  • Active liver disease or unexplained persistent elevations of serum transaminases
  • History of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors

Side Effects

  • Constipation
  • Flatulence
  • Dyspepsia
  • Headache
  • Infection
  • Back pain
  • Rash
  • Asthenia
  • Arthralgia
  • Myalgia

Pregnancy & Lactation

  • Contraindicated during pregnancy
  • Safety not established in pregnant women
  • Potential excretion in human milk
  • Potential reduction in fetal levels of mevalonate
  • Contraindicated during breastfeeding

Precautions & Warnings

  • Liver function tests before initiation of treatment and periodically thereafter
  • Caution in patients with substantial alcohol consumption or history of liver disease
  • Discontinue therapy if markedly elevated CPK levels occur or if myopathy is diagnosed or suspected

Use in Special Populations

  • Higher plasma concentrations in healthy elderly subjects
  • No clinically significant difference in LDL-C reduction between men and women
  • No dose adjustment in renal dysfunction patients
  • Markedly increased plasma concentrations in chronic alcoholic liver disease patients

Overdose Effects

  • Specific treatment not available
  • Symptomatic treatment and supportive measures
  • Liver function tests and serum CK levels monitoring
  • Hemodialysis not expected to significantly enhance drug clearance

Therapeutic Class

  • Other Anti-anginal & Anti-ischaemic drugs
  • Statins

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C33H35FN2O5
  • Chemical Structure: Image available

Common Questions about Xerova 40 mg Tablet

  • What is Xerova 40 mg Tablet?
  • How should I take Xerova 40 mg Tablet?
  • What are the uses of Xerova 40 mg Tablet?
  • What are the Side Effects of Xerova 40 mg Tablet?
  • What are the instructions for storage and disposal Xerova 40 mg Tablet?
  • Is Xerova 40 mg Tablet used for lowering cholesterol?
  • Will taking Xerova 40 mg Tablet increase my risk of diabetes?
  • For how long do I need to take Xerova 40 mg Tablet? Is it safe for long-term use?
  • Does Xerova 40 mg Tablet cause weight loss?
  • Can I stop taking Xerova 40 mg Tablet?
  • Does Xerova 40 mg Tablet cause memory loss?
  • Does Xerova 40 mg Tablet make you tired?
  • Can Xerova 40 mg Tablet be prescribed to children?
  • Is Xerova 40 mg Tablet a blood thinner?
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