DOBUTamine Hameln 250 mg/50 ml (IV Injection)
50 ml vial: ৳ 1,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Dobutamine hydrochloride |
| Company | Siegfried hameln germany |
Indications
- Treatment of hypoperfusion states
- Inotropic support
- Treatment of abnormally increased ventricular filling pressures
- Risk of pulmonary congestion and oedema
Pharmacology
- Direct-acting inotropic agent
- Stimulation of cardiac adrenergic receptors
- Mild chronotropic effects
- Hypertensive effects
- Arrhythmogenic effects
- Vasodilatory effects
- Increases stroke volume and cardiac output
- Decreases ventricular filling pressure
- Decreases total systemic and pulmonary vascular resistances
Dosage & Administration
- Continuous intravenous infusion
- Short half-life
- No loading doses or bolus injections required
- Recommended dosage based on patient response and haemodynamic parameters
- Concentration and volume adjustment based on patient's fluid requirements
- Gradual dosage decrease advised for discontinuation
Interaction
- Potential decreased potency with b-adrenergic receptor antagonists
- Unopposed a-agonist effects in case of b-adrenergic receptor blockade
- No overt indication of interactions with other medicines
Contraindications
- Hypersensitivity to Dobutamine Hydrochloride
Side Effects
- Affecting heart rate, blood pressure, and ventricular ectopic activity
- Hypotension
- Reactions at sites of intravenous infusion
- Miscellaneous effects
Pregnancy & Lactation
- Not recommended during pregnancy unless benefits outweigh risks
- Caution advised during nursing
- Breastfeeding discontinuation during dobutamine treatment
Precautions & Warnings
- Close monitoring of heart rate, rhythm, arterial blood pressure, and infusion rate
- Electrocardiographic monitoring during therapy initiation
Therapeutic Class
- Inotropic-sympathomimetics
Storage Conditions
- Store below 30°C
- Away from light and moisture
- Keep out of the reach of children