Carbofer 500 mg/10 ml (IV Injection or Infusion)
10 ml vial: ৳ 700.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ferric carboxymaltose |
| Company | Chemist laboratories ltd |
Title
- Carbofer
Categories
- Medical Supplies
- Pharmaceuticals
Description
- Colloidal iron (III) hydroxide in complex with Carboxymaltose, a Carbohydrate polymer that releases iron.
Indications
- Treatment of iron deficiency anaemia in adult patients
- Intolerance to oral iron
- Non-dialysis dependent chronic kidney disease
Dosage & Administration
- Stepwise approach for determination of the individual iron need and calculation and administration of the iron dose(s)
Interaction
- No formal drug interaction studies performed
Contraindications
- Hypersensitivity to the active substance or any of its excipients
- Serious hypersensitivity to other parenteral iron products
- Anaemia not attributed to iron deficiency
- Evidence of iron overload or disturbances in the utilisation of iron
Side Effects
- Nausea
- Headache
- Dizziness
- Hypertension
- Injection site reactions
- Nausea
- Increased alanine aminotransferase
- Hypophosphataemia
- Hypersensitivity
- Dysgeusia
- Tachycardia
- Hypotension
- Flushing
- Dyspnoea
- Dyspepsia
- Abdominal pain
- Constipation
- Diarrhea
- Pruritus
- Urticaria
- Erythema
- Rash
- Myalgia
- Back pain
- Arthralgia
- Muscle spasms
- Pyrexia
- Fatigue
- Chest pain
- Peripheral edema
- Chills
- Increased aspartate aminotransferase
- Increased gamma glutamyl transferase
- Increased blood lactate dehydrogenase
- Increased blood alkaline phosphatase
- Anaphylactoid reactions
- Loss of consciousness
- Anxiety
- Phlebitis
- Syncope
- Presyncope
- Bronchospasm
- Flatulence
- Angioedema
- Pallor
- Face edema
- Rigors
- Malaise
- Influenza-like illness
Pregnancy & Lactation
- No adequate and well-controlled trials in pregnant women
- Animal data suggest that iron released from Ferric Carboxymaltose can cross the placental barrier
- Use confined to the second and third trimester if benefit is judged to outweigh the potential risk
- Unlikely to represent a risk to the breast-fed child based on limited data on breastfeeding women
Precautions & Warnings
- Serious hypersensitivity reactions reported
- Monitor for signs and symptoms of hypersensitivity
- Administer only when personnel and therapies are immediately available for the treatment of serious hypersensitivity reactions
- Transient elevations in systolic blood pressure may occur
- Laboratory assays may overestimate serum iron and transferrin bound iron
Use in Special Populations
- A single maximum daily injection dose of 200 mg iron should not be exceeded in haemodialysis-dependent chronic kidney disease patients
- Not recommended in children under 14 years
Overdose Effects
- Excessive dosages may lead to accumulation of iron in storage sites potentially leading to hemosiderosis
- Monitoring of iron parameters advised
- Treat according to standard medical practice if iron accumulation has occurred
Therapeutic Class
- Parenteral Iron Preparations
Storage Conditions
- Cool & dry place, away from light
- Do not freeze
- Keep out of the reach of children