C-Fenac Plus (75 mg+20 mg)/2 ml (IM Injection)

2 ml ampoule: ৳ 15.00 (4 x 5: ৳ 300.00)

Medicine Details

Category Details
Generic Diclofenac sodium lidocaine hydrochloride
Company Chemist laboratories ltd

Indications

  • Relieves pain and inflammation in arthritic conditions
  • Relieves pain in musculoskeletal disorders
  • Treats trauma-induced pain
  • Relieves pain in renal colic

Pharmacology

  • Potent nonsteroidal antiinflammatory drug (NSAID)
  • Has analgesic and antipyretic properties
  • Inhibits prostaglandin synthesis
  • Has uricosuric effects
  • Lidocaine acts as a local anaesthetic

Dosage & Administration

  • Adult dosage: one ampoule once daily by intramuscular injection
  • Renal colic dosage: one ampoule once daily intramuscularly, may repeat after 30 minutes if necessary
  • Recommended dosage for children and elderly patients

Interaction

  • May increase plasma concentrations of Lithium and Digoxin
  • Reports of increased risk of haemorrhage with anticoagulant therapy
  • Can be given together with oral antidiabetic agents without influencing their clinical effect
  • Cases of nephrotoxicity with concomitant use of Cyclosporin
  • Potential of serious toxicity when used with Methotrexate
  • Caution needed when considering concomitant therapy with quinolones
  • Increased frequency of unwanted effects with other NSAIDs and steroids
  • Inhibition of diuretic activity with various NSAIDs

Contraindications

  • Hypersensitivity to Diclofenac or local anaesthetics
  • Active or suspected peptic ulcer or gastrointestinal bleeding
  • Incidence of hypersensitive reactions to specific excipients

Side Effects

  • Mild and transient gastrointestinal discomfort, nausea, diarrhea, and bleeding
  • Rare instances of injection site disorder, abscesses, and local necrosis
  • Adverse effects due to Lidocaine mainly involve the CNS and are dose related

Pregnancy & Lactation

  • Not recommended unless compelling reasons exist
  • Lowest effective dosage should be used
  • Not recommended during the last trimester of pregnancy
  • Small quantities may be detected in breast milk with no expected undesirable effects on the infant

Precautions & Warnings

  • Close observation for patients with severe hepatic, cardiac, or renal insufficiency or the elderly
  • Renal function monitoring for patients using NSAIDs
  • Discontinuation if abnormal liver function tests persist or worsen
  • Monitoring of all patients receiving long term treatment with NSAIDs

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Store at temperature not exceeding 30°C in a dry place
  • Protected from light

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