Ezygo 10 mg (Tablet)

Unit Price: ৳ 10.00 (5 x 10: ৳ 500.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Sodium picosulfate
Company Ibn sina pharmaceuticals ltd
Also available as
Ezygo 5 mg oral solution

Indications

  • Constipation of any etiology
  • Relief from prolonged & recurrent constipation
  • Bowel clearance before surgery, childbirth or radiological investigations.

Pharmacology

Sodium Picosulfate is a triarylmethane group derivative stimulant laxative. After oral administration, it is activated by the colonic bacteria and acts locally in the colon. The active form then stimulates the nerve endings of the intestinal wall and results in colonic peristalsis with promotion of accumulation of water and electrolytes in the colonic lumen. This results in stimulation of defecation, reduction of transit time and softening of the stool. Stimulation of the rectum causes increased motility and a feeling of rectal fullness. The rectal effect may help to restore the 'call to stool'.

Dosage & Administration

  • 10 mg tablet dose:
    • Adults and children over 10 years of age: 5-10 mg per day
    • Children aged 4-10 years: 2.5-5 mg per day
  • Oral Solution (5 mg/5 ml) dose:
    • Adults and children over 10 years of age: 5-10 ml or one to two teaspoonful per day
    • Children aged 4-10 years: 2.5-5 ml or half to one teaspoonful per day
    • Children from One month to 4 years of age: 0.25 ml/kg body weight per day
  • Concentrated Oral Solution (7.5 mg/ml) dose:
    • Adults and children over 10 years of age: 0.67-1.33 ml per day
    • Children aged 4-10 years: 0.33-0.67 ml per day

Interaction

The concomitant use of diuretics or adreno-corticosteroids may increase the risk of electrolyte imbalance if excessive doses are taken. Concurrent administration of antibiotics may reduce the laxative action of Ezygo.

Contraindications

  • Ileus or intestinal obstruction
  • Severe painful and/or feverish acute abdominal conditions (e.g. appendicitis) potentially associated with nausea and vomiting
  • Acute inflammatory bowel diseases
  • Severe dehydration
  • Known hypersensitivity to Sodium Picosulfate or any other component of the product

Side Effects

  • Hypersensitivity
  • Dizziness
  • Syncope
  • Vasovagal response
  • Gastrointestinal disorders
  • Diarrhea
  • Abdominal pain and abdominal cramps
  • Nausea
  • Vomiting

Pregnancy & Lactation

There are no reports of undesirable or damaging effects during pregnancy or to the foetus attributable to the use of this product. Use of the drug should be avoided during the first trimester. Clinical data show that neither the active moiety of sodium Picosulfate (BHPM or bis-(p hydroxyphenyl)-pyridyl-2-methane) nor its glucuronides are excreted into the milk of healthy lactating females.

Precautions & Warnings

Prolonged excessive use may lead to fluid and electrolyte imbalance and hypokalemia. Harmful for those suffering from alcoholism. To be taken into account in pregnant or breast-feeding women, children and high-risk groups such as patients with liver disease or epilepsy.

Overdose Effects

Laxatives when taken in chronic overdosage may cause chronic diarrhea, abdominal pain, hypokalemia, secondary hyperaldosteronism, and renal calculi. Renal tubular damage, metabolic alkalosis, and muscle weakness secondary to hypokalemia have also been described in association with chronic laxative abuse.

Therapeutic Class

Stimulant Laxative

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Chemical Structure

  • Molecular Formula: C18H15NNa2O9S2
  • Chemical Structure Image URL: https://medex.com.bd/storage/res/g-res-1480-sodium-picosulfate-chemical-structure-VXribBHk7yHHQxt7umhH.svg

Common Questions about Ezygo 10 mg Tablet

  • What is Ezygo 10 mg Tablet?: Ezygo 10 mg Tablet belongs to the class of laxatives.
  • What are the uses of the Ezygo 10 mg Tablet?: Ezygo 10 mg Tablet is used in the treatment of constipation.
  • How long do I need to use Ezygo 10 mg Tablet before I see improvement in my condition?: Ezygo 10 mg Tablet is to be taken till the time you see an improvement in your health conditions.
  • At what frequency do I need to use Ezygo 10 mg Tablet?: Ezygo 10 mg Tablet should be taken in the dosage as prescribed by the doctor.
  • Should I use Ezygo 10 mg Tablet empty stomach, before food or after food?: Ezygo 10 mg Tablet should be taken at bed-time as it requires 6-8 hours to show effect.
  • What are the instructions for the storage and disposal of Ezygo 10 mg Tablet?: Ezygo 10 mg Tablet should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.
  • Is Ezygo 10 mg Tablet safe for pregnant women?: Ezygo 10 mg Tablet is not prescribed to pregnant women unless necessary. Consult your doctor beforehand.
  • Is Ezygo 10 mg Tablet safe for breastfeeding women?: Breastfeeding women are not suggested to take Ezygo 10 mg Tablet unless necessary. Consult your doctor beforehand.
  • Is Ezygo 10 mg Tablet a habit forming drug?: No case of addiction has been reported yet.
  • What if I miss a dose of Ezygo 10 mg Tablet?: Take Ezygo 10 mg Tablet as soon as you remember. However, stick to your routine if it's the time for the next dose. Do not double the dose.
  • Quick Tips:
    • Together with Ezygo 10 mg Tablet, taking a fiber-rich diet containing whole grain bread and cereals, bran, fruits and green leafy vegetables, is essential to maintain healthy bowel function.
    • Avoid taking a Ezygo 10 mg Tablet for more than 1 week, unless prescribed by the doctor, as it leads to dependency on the laxative action to produce a bowel movement.
    • Take Ezygo 10 mg Tablet after 2 hours from other medicines, as it may interfere with the absorption of other medicines.
    • Ezygo 10 mg Tablet should be preferably taken at bedtime because it requires 6 to 8 hours to show impact.

Related Brands