Kelac 60 mg/2 ml (IM/IV Injection)
2 ml ampoule: ৳ 95.00 (1 x 4: ৳ 380.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Chemist laboratories ltd |
| Also available as |
Indications
- Short-term management of moderate to severe acute post-operative pain
- Relief of pain, inflammation, and light sensitivity after ocular surgery
- Decrease eye inflammation or redness caused by seasonal allergies
Description
- Belongs to pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAID)
- Inhibits synthesis of prostaglandins
- Peripherally acting analgesic
- Highly protein bound
- Largely metabolized in the liver
Pharmacology
- Inhibits cyclooxygenase enzyme system
- Minimal anti-inflammatory effect at analgesic dose
Dosage & Administration
- Recommended tablet dose: 10 mg every 4-6 hours for up to 7 days
- Recommended injection dose: varies by age and condition, given either as single or multiple doses
- Eye drops: recommended 1 drop in each eye 4 times daily
Interaction
- Increased side effects with other NSAIDs or aspirin
- Enhanced anti-coagulant effect with anti-coagulants
- Reduced anti-hypertensive effect with Beta Blocker
- Increased risk of renal impairment with ACE Inhibitors
- Enhanced toxicity of methotrexate
Contraindications
- Hypersensitivity to the drug or other NSAIDs
- Age under 16 years
- Prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Melena
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in females
- Pulmonary edema
Pregnancy & Lactation
- FDA Pregnancy category C
- Avoid in pregnancy and lactation unless potential benefits outweigh risks to the fetus
Precautions & Warnings
- Caution in patients over 65 years
- Caution in patients with active or suspected peptic ulcer or gastrointestinal bleeding, asthma, and liver dysfunction
- Discontinue use in patients with evidence of corneal epithelial breakdown
- Do not administer while wearing contact lenses
Therapeutic Class
- Drugs used for Rheumatoid Arthritis
- Non-opioid analgesics
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children