Vitamin-B1 100 mg/ml (IM/IV Injection)

1 ml ampoule: ৳ 3.50 (50's pack: ৳ 175.00)

Medicine Details

Indications

  • Treatment of thiamine deficiency manifestations
  • Treatment of Beriberi and Wernick's encephalopathy
  • Neuritis associated with pregnancy
  • Treatment of pellagra

Pharmacology

  • Coenzyme for decarboxylation of α-ketoglutaric acid
  • Affects peripheral nervous system, gastrointestinal tract, and cardiovascular system
  • Necessary for optimal growth of infants and children
  • Not stored in the body and regularly lost during deficiency

Dosage & Administration

  • Prophylaxis: 3 to 10 mg daily
  • Mild chronic deficiency: 10 to 25 mg daily
  • Severe deficiency: 200 to 300 mg daily

Interaction

  • Acts synergistically with other B-complex vitamins
  • Reduces potential for adverse effects
  • No hazardous drug interactions reported

Contraindications

  • Increased risk of anaphylaxis with repeated parenteral administration
  • Start a second course with a considerably lower dose to avoid anaphylactic shock
  • Avoid intravenous administration except in comatose patients

Side Effects

  • Anaphylactic reactions after intravenous administration in sensitive patients
  • Transient mild soreness at the site of intramuscular administration

Pregnancy & Lactation

  • Safe for neonates, children, pregnant and lactating women, and elderly patients

Therapeutic Class

  • Vitamin-B preparations

Storage Conditions

  • Protect from light and moisture

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