Anulid 400 mg (Tablet)
Unit Price: ৳ 60.00 (2 x 10: ৳ 1,200.00)
Strip Price: ৳ 600.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Linezolid |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of nosocomial pneumonia
- Treatment of community-acquired pneumonia
- Treatment of complicated skin and skin structure infection
- Treatment of uncomplicated skin and skin structure infections
- Treatment of vancomycin-resistant Enterococcus faecium infections
Pharmacology
- Oxazolidinone class of antibiotics
- Inhibits bacterial protein synthesis
- Bacteriostatic against enterococci and staphylococci
- Bactericidal for most strains of streptococci
Dosage & Administration
- Oral administration with or without food
- Intravenous infusion over 30 to 120 minutes
- Different dosages for pediatric and adult patients
- Duration of treatment varies with different infections
- No dose adjustment necessary when switching from intravenous to oral
Interaction
- Reversible, nonselective inhibitor of monoamine oxidase
- Potential interaction with adrenergic and serotonergic agents
- Patients should avoid large quantities of tyramine-rich foods/beverages
Contraindications
- Hypersensitivity to Linezolid or any product components
- Concurrent use with monoamine oxidase inhibitors
- Uncontrolled hypertension, pheochromocytoma, or thyrotoxicosis
- Use with sympathomimetic, vasopressive, or dopaminergic agents
Side Effects
- Mostly mild to moderate adverse events
- Common adverse events include diarrhea, headache, and nausea
- Other adverse events such as hypertension, dyspepsia, and localized abdominal pain
Pregnancy & Lactation
- Potential benefit versus risk should be considered during pregnancy
- Linezolid presence in breast milk
- Breastfed infants should be monitored for diarrhea and vomiting
Precautions & Warnings
- Weekly monitoring of complete blood counts
- Prompt ophthalmic evaluation if visual impairment symptoms occur
- Not approved for treatment of catheter-related bloodstream infections
- Clostridium difficile-associated Diarrhea (CDAD) precautions
- Monitor for potential increases in blood pressure
Overdose Effects
- No reported cases of overdose
- Symptomatic and supportive care recommended
- Approximately 30% of dose removed during 3 hours of hemodialysis
Therapeutic Class
- Macrolides
Reconstitution
- Shake oral suspension bottle to loosen powder
- Add boiled and cooled water to dry mixture for oral suspension
- Shake well before each use of reconstituted suspension
- Ready-to-use infusion bottles for intravenous administration
Storage Conditions
- Store at room temperature (15°C-30°C) away from light and moisture