Moxilocin 0.5% (Ophthalmic Ointment)

5 gm tube: ৳ 130.00

Medicine Details

Category Details
Generic Moxifloxacin hydrochloride ophthalmic
Company Opsonin pharma ltd
Also available as
Moxilocin 05 eye drop

Indications

  • Treatment of bacterial conjunctivitis caused by susceptible strains of specified organisms
  • Highly effective intraocular antibiotic to prevent postoperative bacterial endophthalmitis

Pharmacology

  • Antimicrobial action from inhibition of topoisomerase II and IV
  • Involvement in replication, transcription, and repair of bacterial DNA

Dosage & Administration

  • Eye Drops: One drop in the affected eye 3 times per day for 7 days
  • Eye Ointment: Thin and even application three times a day for first two days, and then two times a day for the next five days or as advised
  • Intraocular injection: Administered as 0.2-0.4 ml dose prior to ocular surgery via intraocular route

Interaction

  • Does not inhibit CYP3A4, CYP2D6, CYP2C9, CYP2C19, or CYP1A2
  • Unlikely to alter the pharmacokinetics of drugs metabolized by these cytochrome P450 isozymes

Contraindications

  • Contraindicated in patients with history of hypersensitivity to Moxifloxacin, quinolones, or any components in medication

Side Effects

  • Ocular adverse events: conjunctivitis, decreased visual acuity, dry eye, etc.
  • Nonocular adverse events: fever, increased cough, infection, rash, etc.

Pregnancy & Lactation

  • Use during pregnancy only if potential benefit justifies potential risk to fetus
  • Caution when administered to a nursing mother

Precautions & Warnings

  • Prolonged use may result in overgrowth of nonsusceptible organisms, including fungi
  • Discontinue if superinfection occurs and institute alternative therapy
  • Examination with aid of magnification when necessary
  • Patient advised not to wear contact lenses with signs and symptoms of bacterial conjunctivitis

Therapeutic Class

  • Ophthalmic antibacterial drugs

Storage Conditions

  • Store below 25°C
  • Do not freeze
  • Store in cool and dry place, protected from light
  • Keep out of the reach of children
  • Do not touch dropper tip to any surface
  • Do not use after one month of first opening

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