Rivarin 200 mg (Capsule)
Unit Price: ৳ 30.00 (6 x 10: ৳ 1,800.00)
Strip Price: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ribavirin |
| Company | Healthcare pharmaceuticals ltd |
Indications
- Treatment of chronic hepatitis C virus infection
- Combination therapy with other antiviral drugs
- Treatment in patients with compensated liver disease
- Treatment in adult patients coinfected with HIV
Pharmacology
- Synthetic nucleoside
- Inhibitory action against respiratory syncytial virus
- Inhibitory action against influenza virus
- Inhibitory action against herpes simplex virus
- Mechanism of action not clear
- Interference with viral nucleic acid synthesis
- Responsible for antiviral action
Dosage & Administration
- Recommended duration of treatment
- Assessment of virologic response after 24 weeks
- Treatment discontinuation criteria
- Safety and efficacy data for different patient populations
- Administration without regard to food
- Increased water consumption during treatment
Interaction
- Potential interaction with nucleoside reverse transcriptase inhibitors
- Recommendations for dose reduction or discontinuation
- Concomitant use with azathioprine reported effects
- Increased risk of pancytopenia with azathioprine
Contraindications
- Contraindicated in pregnant women
- Potential fetal harm
- Contraindicated in patients with hemoglobinopathies
- Reports of fatal hepatic failure in combination with didanosine
Side Effects
- Common adverse reactions in adults
- Psychiatric and central nervous system effects
- Ocular disorder
- Dental and periodontal disorders
- Growth inhibition in children and adolescents
- Irreversible effects in some patients
Pregnancy & Lactation
- Category X for pregnancy
- Embryocidal and teratogenic effects in animal studies
- Adverse effects in nursing infants
- Potential excretion in human milk
- Recommendation to discontinue nursing if on therapy
Precautions & Warnings
- Strict avoidance in pregnancy and post-treatment
- Requirement of negative pregnancy test prior to therapy
- Use of contraception and monthly pregnancy tests
- Guidelines for male patients with partners
- Limitation on sexual activity with pregnant women
Use in Special Populations
- Absence of established use in pediatric patients below 3 years
- Heightened risk in geriatric patients
- Dose adjustment based on renal function
Therapeutic Class
- Hepatic viral infections (Hepatitis C)
Storage Conditions
- Keep out of reach of children
- Storage in cool and dry place
- Protection from light