Etopor 100 mg/5 ml (IV Infusion)
100 mg vial: ৳ 400.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Etoposide |
| Company | Eskayef pharmaceuticals ltd |
Indications
- Small Cell Lung Cancer
- First-line treatment
- Approved chemotherapeutic agents
Pharmacology
- Semisynthetic derivative
- Podophyllotoxin derivatives
- Inhibits mitosis
- Inhibits cell cycle progression
Pharmacokinetics
- Biphasic process
- Distribution half-life
- Terminal elimination half-life
- Total body clearance values
- Plasma concentration vs time curves
- Volumes of distribution at steady state
Dosage & Administration
- Dose ranges
- Impaired renal function dosage modification
- Creatinine clearance
- Subsequent dosing based on tolerance and clinical effect
Interaction
- High-dose cyclosporine a interaction
- Laboratory tests requirement
Contraindications
- Hypersensitivity
- Previous hypersensitivity
Side Effects
- Myelosuppression
- Granulocyte nadirs
- Platelet nadirs
- Nausea and vomiting
- Mucositis
- Hypotension
- Allergic reactions
- Anaphylactic-like reactions
- Hematologic toxicity
- Gastrointestinal toxicity
- Other toxicities
Pregnancy & Lactation
- Pregnancy category D
- No adequate and well controlled studies
- Etoposide found in human milk
- Breastfeeding not recommended
Precautions & Warnings
- Myelosuppression observation
- Dose limiting bone marrow suppression
- Platelet count monitoring
- Anaphylactic reaction
- Concentration of infusion impact
- Symptomatic treatment
- Intravenous infusion recommendation
- Risk evaluation
- Adverse reactions reversibility
- Low serum albumin risk
Therapeutic Class
- Cytotoxic Chemotherapy
Storage Conditions
- Refrigeration required
- Stability under refrigeration
- 24 months stability
- Protection from light
- Proper handling and disposal procedure