PG CR 82.5 mg (Tablet (Controlled Release))

Unit Price: ৳ 25.00 (2 x 10: ৳ 500.00)
Strip Price: ৳ 250.00

Medicine Details

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

  • Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
  • Binds with high affinity to the alpha2-delta site in central nervous system tissues

Dosage

  • Maximum recommended dose of Pregabalin is 100 mg three times a day
  • Dose range for postherpetic neuralgia is 75 to 150 mg two times a day or 50 to 100 mg three times a day

Administration

  • Route of administration: Oral route
  • Pregabalin CR tablet should be administered after an evening meal
  • Swallowed whole and should not be split, crushed, or chewed

Interaction

  • Unlikely to be involved in significant pharmacokinetic drug interactions

Contraindications

  • Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components

Side Effects

  • Common side effects in adults include dizziness, somnolence, dry mouth, edema, blurred vision, weight gain
  • Common side effects in pediatric patients include increased weight and increased appetite

Pregnancy & Lactation

  • No adequate and well-controlled studies with pregabalin in pregnant women
  • Small amounts detected in the milk of lactating women
  • Breastfeeding not recommended due to potential risk of tumorigenicity

Precautions & Warnings

  • Angioedema can occur and may be associated with life-threatening respiratory compromise
  • Increased risk of suicidal thoughts or behavior
  • Respiratory depression may occur when used with concomitant CNS depressants
  • May cause dizziness, somnolence, impair ability to drive or operate machinery

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients for various indications
  • Safety and effectiveness not established for pediatric patients below the age of 1 month

Overdose Effects

  • Signs and symptoms include reduced consciousness, depression/anxiety, seizures
  • No specific antidote

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage Conditions

  • Keep in a cool & dry place (below 30°C), protected from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C8H17NO2

Common Questions

  • What is PG CR 82.5 mg CR Tablet?
  • How long do I need to use PG CR 82.5 mg CR Tablet before I see improvement?
  • At what frequency do I need to use PG CR 82.5 mg CR Tablet?
  • Should I use PG CR 82.5 mg CR Tablet empty stomach, before food or after food?
  • What are the instructions for the storage and disposal of PG CR 82.5 mg CR Tablet?
  • Does PG CR 82.5 mg CR Tablet work in the same way for each disease?
  • How long do I need to take PG CR 82.5 mg CR Tablet?
  • Is it necessary to continue taking PG CR 82.5 mg CR Tablet even if I feel fine?
  • Can I take Diazepam and PG CR 82.5 mg CR Tablet together?
  • Can the use of PG CR 82.5 mg CR Tablet cause weight gain?
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