Cardicil 5 mg (Tablet)
Unit Price: ৳ 7.00 (3 x 14: ৳ 294.00)
Strip Price: ৳ 98.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cilnidipine |
| Company | Radiant pharmaceuticals ltd |
| Also available as |
Indications
- Management of hypertension for end-organ protection
- Useful in elderly patients
- Useful in patients with diabetes and albuminuria
- Use in patients with chronic kidney disease
Pharmacology
- Dihydropyridine calcium-channel blocker
- Binds to dihydropyridine binding sites of L-type voltage dependent calcium channel
- Inhibits Ca2+ influx across vascular smooth muscle cells
- Causes vasodilation
- Inhibits Ca2+ influx via N-type voltage dependent calcium channels in sympathetic nerve cell membrane
Dosage & Administration
- Adults: 5-10 mg once daily after breakfast
- Maximum dose: 20 mg once daily
- Pediatric use not established
- Initiate therapy in elderly with lowest possible dose (5 mg)
Interaction
- Potential interactions with other anti-hypertensive medications
- Potential interactions with antipsychotics causing hypotension
- Potential interactions with quinidine, carbamazepine, phenytoin, rifampicin, cimetidine, erythromycin
Contraindications
- Known sensitivity to Cilnidipine or any of the excipients
- Cardiogenic shock
- Recent MI or acute unstable angina
- Severe aortic stenosis
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral oedema
- Palpitations
- GI disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Depression
Pregnancy & Lactation
- Avoid administration in pregnant or potentially pregnant women
- Avoid administration to nursing mothers
- If administration is indispensable, instruct patient to discontinue lactation
Precautions & Warnings
- Administer with care in patients with serious hepatic dysfunction
- Administer with care in patients with a history of serious adverse reactions to calcium antagonists
- Gradually decrease dosage during discontinuation under close observation
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Store below 30°C
- Protected from light and moisture
- Keep away from reach of children