Nafinex 2% (Cream)
10 gm tube: ৳ 80.00
Medicine Details
Category | Details |
---|---|
Generic | Naftifine hydrochloride |
Company | Everest pharmaceuticals ltd |
Indications
- Treatment of interdigital tinea pedis
- Treatment of tinea cruris
- Treatment of tinea corporis
- Caused by Trichophyton rubrum
Description
- Synthetic antifungal agent
- Allylamine derivative
- Broad spectrum activity
- Fungicidal activity against various organisms
- Fungistatic activity against Candida species
Pharmacology
- Inhibition of squalene 2,3-epoxidase
- Interference with sterol biosynthesis
- Decreased amounts of sterols
- Accumulation of squalene in the cells
Dosage & Administration
- Topical use only
- Not for ophthalmic, oral, or intravaginal use
- Once-daily application
- 2 weeks treatment duration
Side Effects
- Common adverse reaction: pruritus
Pregnancy & Lactation
- Pregnancy Category B
- No adequate and well-controlled studies in pregnant women
- Use during pregnancy only if benefit justifies risk
- Unknown excretion in human milk
Precautions & Warnings
- Discontinue if redness or irritation develops
Use in Special Populations
- Established safety and effectiveness in age group 12-17
- Safety and effectiveness not established in pediatric patients <12 years
- Limited studies in subjects aged 65 and over
Therapeutic Class
- Topical Antifungal preparations
Storage Conditions
- Store at 25°C
- Excursions permitted to 15-30°C