Vcent 50 mg (Tablet)

Unit Price: ৳ 50.00 (1 x 10: ৳ 500.00)
Strip Price: ৳ 500.00

Medicine Details

Category Details
Generic Voriconazole
Company Pharmasia limited
Also available as

Indications

  • Invasive aspergillosis
  • Candidemia (nonneutropenic) and disseminated candidiasis
  • Esophageal candidiasis
  • Serious infections caused by Scedosporium apiospermum and Fusarium Species
  • Intolerance or refractory to other therapy

Pharmacology

  • Triazole antifungal medication
  • Inhibition of ergosterol synthesis
  • Inhibition of CYP450-dependent 14-alpha sterol demethylase

Dosage & Administration

  • Oral and Injection administration
  • Different dosage for body weight groups
  • Loading dose regimen
  • Maintenance dose regimen

Interaction

  • CYP3A4, CYP2C9, and CYP2C19 inhibitors and inducers
  • Increase in concentration and activity of drugs
  • Coadministration of Phenytoin or Efavirenz

Contraindications

  • Known hypersensitivity to Voriconazole or any other components
  • Co-administration with specific drugs
  • Risk of serious adverse reactions or loss of efficacy

Side Effects

  • Abdominal pain
  • Anemia
  • Blurred vision
  • Headache
  • Chest pain
  • Nausea
  • Diarrhea

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Use during pregnancy if potential benefit justifies potential risk to the fetus

Precautions & Warnings

  • Careful assessment of benefit-risk balance for long-term exposure
  • Reported cases of squamous cell carcinoma of the skin

Use in Special Populations

  • Efficacy not established for children under 12 years of age

Overdose Effects

  • No data available

Therapeutic Class

  • Other Antifungal preparations

Reconstitution

  • Instructions for suspension reconstitution
  • Shake the bottle well before adding water
  • Store reconstituted suspension between 15°C-30°C
  • Discard suspension 14 days after reconstitution

Storage Conditions

  • Keep out of reach of children
  • Store in a dry place below 25°C and protected from light
  • Store Vcent powder for suspension between 2°C to 8°C

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