Vcent 50 mg (Tablet)
Unit Price: ৳ 50.00 (1 x 10: ৳ 500.00)
Strip Price: ৳ 500.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Voriconazole |
| Company | Pharmasia limited |
| Also available as |
Indications
- Invasive aspergillosis
- Candidemia (nonneutropenic) and disseminated candidiasis
- Esophageal candidiasis
- Serious infections caused by Scedosporium apiospermum and Fusarium Species
- Intolerance or refractory to other therapy
Pharmacology
- Triazole antifungal medication
- Inhibition of ergosterol synthesis
- Inhibition of CYP450-dependent 14-alpha sterol demethylase
Dosage & Administration
- Oral and Injection administration
- Different dosage for body weight groups
- Loading dose regimen
- Maintenance dose regimen
Interaction
- CYP3A4, CYP2C9, and CYP2C19 inhibitors and inducers
- Increase in concentration and activity of drugs
- Coadministration of Phenytoin or Efavirenz
Contraindications
- Known hypersensitivity to Voriconazole or any other components
- Co-administration with specific drugs
- Risk of serious adverse reactions or loss of efficacy
Side Effects
- Abdominal pain
- Anemia
- Blurred vision
- Headache
- Chest pain
- Nausea
- Diarrhea
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Use during pregnancy if potential benefit justifies potential risk to the fetus
Precautions & Warnings
- Careful assessment of benefit-risk balance for long-term exposure
- Reported cases of squamous cell carcinoma of the skin
Use in Special Populations
- Efficacy not established for children under 12 years of age
Overdose Effects
- No data available
Therapeutic Class
- Other Antifungal preparations
Reconstitution
- Instructions for suspension reconstitution
- Shake the bottle well before adding water
- Store reconstituted suspension between 15°C-30°C
- Discard suspension 14 days after reconstitution
Storage Conditions
- Keep out of reach of children
- Store in a dry place below 25°C and protected from light
- Store Vcent powder for suspension between 2°C to 8°C