Solu-Medrol 40 mg/vial (IM/IV Injection)
40 mg vial: ৳ 460.97
Medicine Details
| Category | Details |
|---|---|
| Generic | Methylprednisolone sodium succinate |
| Company | Pfizer |
| Also available as |
Indications
- Endocrine disorders
- Rheumatic disorders
- Collagen diseases
- Dermatological diseases
- Allergic states
- Ophthalmic diseases
- Gastrointestinal diseases
- Respiratory diseases
- Hematologic disorders
- Neoplastic diseases
- Edematous state
- Tuberculous meningitis
- Trichinosis
- Neurologic or myocardial involvement
- Symptomatic sarcoidosis
- Fulminating or disseminated pulmonary tuberculosis
- Acquired (autoimmune) hemolytic anemia
- Idiopathic thrombocytopenic purpura in adults
- Erythroblastopenia
- Congenital (erythroid) hypoplastic anemia
- Secondary thrombocytopenia in adults
Pharmacology
- Potent anti-inflammatory effects
- Salt-retaining properties
- Excretion within 12 hours
- Influence on carbohydrate, protein, fat, and purine metabolism
- Suppressive effect on the immune response
Dosage & Administration
- IM or IV administration
- Intravenous injection
- Intramuscular injection
- High-dose therapy
- Dosage adjustment for pediatric patients
- Treatment of acute exacerbations of multiple sclerosis
Interaction
- Aminoglutethimide
- Amphotericin B injection and potassium-depleting agents
- Macrolide antibiotics
- Anticholinesterases
- Anticoagulants
- Antidiabetics
- Antitubercular drugs
- Cholestyramine
- Cyclosporine
- Digitalis glycosides
- Estrogens
- Hepatic enzyme inhibitors
- Ketoconazole
- Nonsteroidal anti-inflammatory agents (NSAIDs)
- Skin tests
- Vaccines
Contraindications
- Systemic fungal infections
- Intrathecal administration
- Idiopathic thrombocytopenic purpura
Side Effects
- Fluid and electrolyte disturbances
- Musculoskeletal effects
- Gastrointestinal effects
- Dermatologic effects
- Neurological effects
- Endocrine effects
- Ophthalmic effects
- Others
- Adverse reactions related to parenteral corticosteroid therapy
Pregnancy & Lactation
- Teratogenic in many species
- No adequate and well-controlled studies in pregnant women
- Systemically administered corticosteroids in human milk
Precautions & Warnings
- Sensitive to heat
- Gradual reduction in dosage
- Complications dependent on dose and duration of treatment
- Discontinuation may result in clinical improvement
Use in Special Populations
- Adverse effects in pediatric patients
- Decrease in growth velocity
- Effect on elderly patients
Overdose Effects
- Supportive and symptomatic therapy
Therapeutic Class
- Glucocorticoids
Reconstitution
- Directions for reconstitution
- Aseptic addition of water for injection
- Agitation to effect solution
- Withdrawal of dose
Storage Conditions
- Protect from light
- Store at controlled room temperature
- Use solution within 48 hours after mixing