Cazep 100 mg/5 ml (Oral Suspension)
100 ml bottle: ৳ 300.90
Medicine Details
| Category | Details |
|---|---|
| Generic | Carbamazepine |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Partial and secondary generalized tonic-clonic seizures
- Primary generalized tonic-clonic seizures
- Trigeminal neuralgia
- Prophylaxis of bipolar disorder
Pharmacology
Carbamazepine depresses activity in the nucleus ventralis of the thalamus, reduces synaptic propagation of excitatory impulses or decreases summation of temporal stimulation leading to neural discharge by limiting influx of Na ions across cell membrane.
Dosage & Administration
- Initial dosage for adults and children over 12 years of age
- Combination therapy
- Trigeminal Neuralgia
Interaction
Galactorrhoea reported in few women on oral contraceptives within the first two months of Cazep treatment
Contraindications
- Problems with the electrical message pathways in the heart (atrioventricular block)
- History of decreased blood cell production by the bone marrow (bone marrow depression)
- Hereditary blood disorders called porphyrias
- Allergy to tricyclic antidepressants
- Use of monoamine-oxidase inhibitor antidepressant (MAOI) in the last 14 days
Side Effects
- Dizziness
- Drowsiness
- Ataxia
- Dry mouth
- Abdominal pain
- Nausea
- Vomiting
- Leucopenia
- Proteinuria
- Bradycardia
- Heart failure
- Hypotension
- Erythematous skin rash
- Aplastic anemia
- Increased sensitivity to the sun
Pregnancy & Lactation
Pregnancy category D. Carbamazepine and its epoxide metabolite are transferred to breast milk. Decision should be made whether to discontinue nursing or discontinue the drug.
Precautions & Warnings
- Drowsiness
- Potentially hazardous activities
- Skin reactions
- Liver problems
- Decreased blood levels of hormonal contraceptives
- Sudden stopping of treatment
- Caution for mixed seizures, elderly people, history of heart disease, kidney disease, liver disease, psychotic illness, raised pressure in the eye, blood disorders, previous Cazep therapy
Therapeutic Class
Primary anti-epileptic drugs
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children